ArticleThe American journal of tropical medicine and hygiene2014
Risk factors for cryptosporidiosis among children in a semi urban slum in southern India: a nested case-control study.
Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Pooled it
- Interventions to improve disposal of child faeces for preventing diarrhoea and soil-transmitted helminth infection.The Cochrane database of systematic reviews · 2019Pooled it
- Anthroponotic transmission of Cryptosporidium parvum predominates in countries with poorer sanitation: a systematic review and meta-analysis.Parasites & vectors · 2019Pooled it
- Risk factors for Cryptosporidium infection in low and middle income countries: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- Effects of Boiling Drinking Water on Diarrhea and Pathogen-Specific Infections in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.The American journal of tropical medicine and hygiene · 2017Pooled it
- Intestinal parasitic infection among household contacts of primary cases, a comparative cross-sectional study.PloS one · 2019Trial
- Cryptosporidium infection and associated factors among diarrheic children under five years of age in Eastern Ethiopia.PLoS neglected tropical diseases · 2025Article
- Prevalence and molecular characterization of Cryptosporidium spp. in dairy and beef cattle in Shanxi, China.Parasitology research · 2023Article
- Improved household flooring is associated with lower odds of enteric and parasitic infections in low- and middle-income countries: A systematic review and meta-analysis.PLOS global public health · 2023Article
- Molecular Epidemiology of Human Cryptosporidiosis in Low- and Middle-Income Countries.Clinical microbiology reviews · 2021Review
- Benefits and Risks of Smallholder Livestock Production on Child Nutrition in Low- and Middle-Income Countries.Frontiers in nutrition · 2021Review
- Prevalence and Correlates ofOpen forum infectious diseases · 2020Article
- Asymptomatic Intestinal Parasitic Infestations among Children Under Five Years in Selected Communities in the Ho Municipality, Ghana.Ethiopian journal of health sciences · 2020Article
- Observational
- Clinical, environmental, and behavioral characteristics associated with Cryptosporidium infection among children with moderate-to-severe diarrhea in rural western Kenya, 2008-2012: The Global Enteric Multicenter Study (GEMS).PLoS neglected tropical diseases · 2018Observational
- Socio-Behavioral Risk Factors Associated with Cryptosporidiosis in HIV/AIDS Patients Visiting the HIV Referral Clinic at Cape Coast Teaching Hospital, Ghana.The open AIDS journal · 2018Article
- The Influence of Household- and Community-Level Sanitation and Fecal Sludge Management on Urban Fecal Contamination in Households and Drains and Enteric Infection in Children.The American journal of tropical medicine and hygiene · 2017Article
- Asparagine-Linked Glycans ofMolecular & cellular proteomics : MCP · 2017Article
- Birth Size, Stunting and Recovery from Stunting in Andhra Pradesh, India: Evidence from the Young Lives Study.Maternal and child health journal · 2017Article
- Natural History of Cryptosporidiosis in a Birth Cohort in Southern India.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
The risk factors for acquisition of cryptosporidial infection in resource-poor settings are poorly understood. A nested case-control study was conducted to assess factors associated with childhood cryptosporidiosis (detected by stool polymerase chain reaction) in an endemic, Indian slum community using data from two community-based studies with 580 children followed prospectively until their second birthday. Factors were assessed for overall cryptosporidiosis (N = 406), and for multiple (N = 208), asymptomatic (N = 243), and symptomatic (N = 163) infections, respectively. Presence of older siblings (odds ratio [OR] = 1.88, P = 0.002) and stunting at 6 months of age (OR = 1.74, P = 0.019) were important risk factors for childhood cryptosporidiosis. Always boiling drinking water before consumption, the use of a toilet by all members of the family, and maternal age ≥ 23 years were protective. These results provide insights into acquisition of childhood cryptosporidiosis in settings with poor environmental sanitation, contaminated public water supply systems, and close human-animal contact. Disease control strategies will require a multifaceted approach.
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Registered trials
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