Evidence map›Paper›PMID 25331776›Full record

ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2014

A scale of socioemotional dysfunction in frontotemporal dementia.

Joseph P Barsuglia, Natalie C Kaiser, Stacy Schantz Wilkins, Simantini J Karve, Robin J Barrows, Pongsatorn Paholpak, Hemali Vijay Panchal, Elvira E Jimenez, Michelle J Mather, Mario F Mendez

Erratum issuedOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Meta-analytic Review of Memory Impairment in Behavioral Variant Frontotemporal Dementia.Journal of the International Neuropsychological Society : JINS · 2018
    Pooled it
  2. Social Cognition in Neurodegenerative Disorders.Dementia and neurocognitive disorders · 2025
    Review
  3. Review
  4. Social Frailty in Late Adulthood: Social Cognitive and Psychological Well-Being Correlates.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Vicarious Embarrassment or "Fremdscham": Overendorsement in Frontotemporal Dementia.The Journal of neuropsychiatry and clinical neurosciences · 2020
    Article
  9. Network Architecture Underlying Basal Autonomic Outflow: Evidence from Frontotemporal Dementia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  10. Review
  11. The attribution of animacy and agency in frontotemporal dementia versus Alzheimer's disease.Cortex; a journal devoted to the study of the nervous system and behavior · 2017
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Joseph P BarsugliaV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA joseph.barsuglia@va.gov joseph.barsuglia@gmail.com.
Natalie C KaiserV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA.
Stacy Schantz WilkinsV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Simantini J KarveV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA.
Robin J BarrowsV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA.
Pongsatorn PaholpakV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA.
Hemali Vijay PanchalV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
Elvira E JimenezV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA.
Michelle J MatherV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA.
Mario F MendezV.A. Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, University of California at Los Angeles, Los Angeles, CA, USA Department of Psychiatry & Biobehavioral Sciences, University of California at Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · USVA Greater Los Angeles Healthcare System · US

Funding

Multidisciplinary Study of Social Behavior and Emotion in Frontotemporal DementiaR01AG034499 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MENDEZ, MARIO F. · 2009 to 2013
$1.9M
NIA NIH HHS R01 AG034499NIA NIH HHS R01AG034499-04
6 · The paper itself

Abstract

Early social dysfunction is a hallmark symptom of behavioral variant frontotemporal dementia (bvFTD); however, validated measures for assessing social deficits in dementia are needed. The purpose of the current study was to examine the utility of a novel informant-based measure of social impairment, the Socioemotional Dysfunction Scale (SDS) in early-onset dementia. Sixteen bvFTD and 18 early-onset Alzheimer's disease (EOAD) participants received standard clinical neuropsychological measures and neuroimaging. Caregiver informants were administered the SDS. Individuals with bvFTD exhibited greater social dysfunction on the SDS compared with the EOAD group; t(32) = 6.32, p < .001. The scale demonstrated preliminary evidence for discriminating these frequently misdiagnosed groups (area under the curve = 0.920, p = <.001) and internal consistency α = 0.977. The SDS demonstrated initial evidence as an effective measure for detecting abnormal social behavior and discriminating bvFTD from EOAD. Future validation is recommended in larger and more diverse patient groups.

Indexed as

AgedAlzheimer DiseaseFemaleFrontotemporal DementiaHumansMaleMiddle AgedPsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsSocial Behavior DisordersBehavioral assessmentDementiaNeurodegenerative diseasesPresenile dementiaSemantic dementiaSocial behavior

Identifiers

PMID25331776
PMCPMC4296158
OpenAlexW1963739180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.