Evidence map›Paper›PMID 25331686›Full record

ArticleArthritis care & research2015

Lower-extremity osteoarthritis and the risk of falls in a community-based longitudinal study of adults with and without osteoarthritis.

Adam L Doré, Yvonne M Golightly, Vicki S Mercer, Xiaoyan A Shi, Jordan B Renner, Joanne M Jordan, Amanda E Nelson

Registry-linked trialAbstract read
In one paragraph

Article in Arthritis care & research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06650865 (Effect of Baduanjin on Pain, Balance and Kinesiophobia in Individuals With Knee Osteoarthritis), which is not on this map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
10.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06650865 nacompletednot on this mapstarted 2024, after this paper: background citation

Effect of Baduanjin on Pain, Balance and Kinesiophobia in Individuals With Knee Osteoarthritis

TypeinterventionalSponsorBiruni UniversityRan2024 to 2025Enrolled60ConditionsOsteoarthritis, KneeArmsTraditional Exercise Group, Baduanjin Exercise Group, Telerehabilitation Group
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 151 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Knee Health Is a Major Determinant of Mobility Across the Healthspan.Journal of functional morphology and kinesiology · 2025
    Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adam L DoréUniversity of North Carolina, Chapel Hill.
Yvonne M Golightly
Vicki S Mercer
Xiaoyan A Shi
Jordan B Renner
Joanne M Jordan
Amanda E Nelson
University of North Carolina at Chapel Hill · US

Funding

Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)KL2TR001109 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$5.7M
UNC Clinical Translation Science Award-K12 Scholars Program (KL2)KL2TR000084 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2012 to 2013
$2.3M
Women's knee motion patterns in functional activitiesP60AR030701 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CALLAHAN, LEIGH FLEMING · 1986 to 2001
$1.9M
Variations in Hip Morphology: Frequency and Impact on Osteoarthritis OutcomesK23AR061406 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NELSON, AMANDA E · 2011 to 2015
$668k
NCATS NIH HHS KL2 TR000084NCATS NIH HHS KL2 TR001109NCATS NIH HHS KL-TR-0084NIAMS NIH HHS 5-P60-AR30701NIAMS NIH HHS K23 AR061406NIAMS NIH HHS K23-AR-1406NIAMS NIH HHS P60 AR030701NIAMS NIH HHS P60 AR049465PHS HHS S043PHS HHS S3486
6 · The paper itself

Abstract

objectiveKnee and hip osteoarthritis (OA) are known risk factors for falls, but whether they together additionally contribute to falls risk is unknown. This study utilizes a biracial cohort of men and women to examine the influence of lower-extremity OA burden on the risk for future falls.

methodsA longitudinal analysis was performed using data from 2 time points of a large cohort. The outcome of interest was falls at followup. Covariates included age, sex, race, body mass index, a history of prior falls, symptomatic OA of the hip and/or knee, a history of neurologic or pulmonary diseases, and current use of narcotic medications. Symptomatic OA was defined as patient-reported symptoms and radiographic evidence of OA in the same joint. Logistic regression analyses were used to determine associations between covariates and falls at followup.

resultsThe odds of falling increased with an increasing number of lower-extremity symptomatic OA joints: those with 1 joint had 53% higher odds, those with 2 joints had 74% higher odds, and those with 3-4 OA joints had 85% higher odds. When controlling for covariates, patients who had symptomatic knee or hip OA had an increased likelihood of falling (adjusted odds ratio [aOR] 1.39, 95% confidence interval [95% CI] 1.02-1.88 and aOR 1.60, 95% CI 1.14-2.24, respectively).

conclusionThis study reveals the risk for falls increases with additional symptomatic OA lower-extremity joints and confirms that symptomatic hip and knee OA are important risk factors for falls.

Indexed as

Accidental FallsAgedAged, 80 and overBlack or African AmericanFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedNorth CarolinaOdds RatioOsteoarthritis, HipOsteoarthritis, KneeRisk AssessmentRisk Factors

Identifiers

PMID25331686
PMCPMC4404178
OpenAlexW1873374913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.