Evidence map›Paper›PMID 25331268›Full record

SynthesisAIDS and behavior2015

Adherence to antiretroviral medications among persons who inject drugs in transitional, low and middle income countries: an international systematic review.

Jonathan Feelemyer, Don Des Jarlais, Kamyar Arasteh, Anneli Uusküla

Abstract readSystematic Review
In one paragraph

Synthesis in AIDS and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. HIV care continuum among men who have sex with men and persons who inject drugs in India: barriers to successful engagement.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan FeelemyerThe Baron Edmond de Rothschild Chemical Dependency Institute, Mount Sinai Beth Israel, 160 Water Street, New York, NY, 10038, USA, jfeelemyer@chpnet.org.
Don Des Jarlais
Kamyar Arasteh
Anneli Uusküla

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan, Courtney McKnight · 1998 to 2026
$38.9M
Multiple HIV Prevention Packages for IDUs in EstoniaR01AI083035 · NIAID · BETH ISRAEL MEDICAL CTR (NEW YORK) · PI DES JARLAIS, DON C · 2009 to 2012
$2.5M
NIAID NIH HHS R01 AI 083035NIAID NIH HHS R01 AI083035NIDA NIH HHS P30 DA011041
6 · The paper itself

Abstract

Adherence to antiretroviral (ART) medication is vital to reducing morbidity and mortality among HIV positive persons. People who inject drugs (PWID) are at high risk for HIV infection in transitional/low/middle income countries (TLMIC). We conducted a systematic review of studies reporting adherence to ART among persons with active injection drug use and/or histories of injection drug use in TLMIC. Meta-regression was performed to examine relationships between location, adherence measurements, and follow-up period. Fifteen studies were included from seven countries. Adherence levels ranged from 33 to 97 %; mean weighted adherence was 72 %. ART adherence was associated with different methods of measuring adherence and studies conducted in Eastern Europe and East Asia. The great heterogeneity observed precludes generalization to TLMIC as a whole. Given the critical importance of ART adherence more research is needed on ART adherence among PWID in TLMIC, including the use of standardized methods for reporting adherence to ART.

Indexed as

Antiretroviral Therapy, Highly ActiveDrug MonitoringBrazilChinaComorbidityDrug UsersEstoniaHIV InfectionsHumansIndiaIndonesiaRussiaSubstance Abuse, IntravenousVietnam

Identifiers

PMID25331268
PMCPMC4393761

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.