Evidence map›Paper›PMID 25331150›Full record

ArticleBMJ case reports2014

A rare case of large cell neuroendocrine carcinoma.

Diwei Lin, Amanda Jia Hui Tan, Agnelo Francis De Sousa, Rajinder Singh-Rai

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. IJU case reports · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Diwei LinDivision of Surgery, Lyell McEwin Hospital, Elizabeth vale, South Australia, Australia.ORCID http://orcid.org/0000-0003-4515-4145
Amanda Jia Hui TanDivision of Surgery, Lyell McEwin Hospital, Elizabeth vale, South Australia, Australia.
Agnelo Francis De SousaDivision of Surgery, Lyell McEwin Hospital, Elizabeth vale, South Australia, Australia.
Rajinder Singh-RaiDivision of Surgery, Lyell McEwin Hospital, Elizabeth vale, South Australia, Australia.
Lyell McEwin Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a very rare case of de novo large cell neuroendocrine carcinoma (LCNEC) of the prostate in an 84-year-old man on a background of high grade, superficially invasive transitional cell carcinoma of the bladder. Pure LCNEC of the prostate is extremely rare. Most LCNEC of the prostate are thought to originate by clonal progression under the selection pressure of therapy and refractory to long-term hormonal treatment for adenocarcinoma of the prostate. De novo LCNEC is only described in case reports and is thought to develop via direct malignant transformation. Limited data in the English literature makes it difficult to accurately predict the prognosis of LCNEC of the prostate. However, current evidence suggesting that increasing neuroendocrine differentiation in prostate adenocarcinoma is associated with a higher stage, high-grade disease and a worse prognosis.

Indexed as

Aged, 80 and overCarcinoma, Large CellCarcinoma, NeuroendocrineCarcinoma, Transitional CellFatal OutcomeHumansMaleNeoplasms, Multiple PrimaryProstateProstatic NeoplasmsTomography, X-Ray ComputedUrinary Bladder Neoplasms

Identifiers

PMID25331150
PMCPMC4208120
OpenAlexW2082619963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.