ReviewNature reviews. Urology2014
Male infertility: a public health issue caused by sexually transmitted pathogens.
Review in Nature reviews. Urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed, 3 syntheses or guidelines pooled it, 238 citations in OpenAlex.
- Microbiota and seminal quality: A systematic review.JBRA assisted reproduction · 2023Pooled it
- Genital mycoplasma infection: a systematic review and meta-analysis.Reproductive health · 2023Pooled it
- Evaluation of the Presence of Bacterial and Viral Agents in the Semen of Infertile Men: A Systematic and Meta-Analysis Review Study.Frontiers in medicine · 2022Pooled it
- Unfolding the Semen Microbiota: Implications for Male Infertility.Biomedicines · 2026Review
- The Influence of Sexually Transmitted Bacteria and Human Papillomavirus on Sperm Parameters: Data from a Preliminary Study.Medicina (Kaunas, Lithuania) · 2026Article
- Human papillomavirus seminal carriage alters virome diversity and male fertility: a case-control study.Reproductive biology and endocrinology : RB&E · 2025Article
- Effect of hepatitis B virus infection in males on pregnancy outcomes of intrauterine insemination.Scientific reports · 2025Article
- Role of Seminal Exosomes in Reproduction.Journal of cellular physiology · 2025Review
- Emerging Neisseria meningitidis ST-1466 and ST-11026 as urogenital pathogens in China.BMC infectious diseases · 2025Article
- Molecular Characterization ofInfectious disease reports · 2025Article
- Infections of chlamydia trachomatis, mycoplasma genitalium and neisseria gonorrhoeae among the outpatients of reproductive medicine center in Chongqing, China: a retrospective study.BMC infectious diseases · 2025Article
- Ureaplasma parvum impaired semen quality improves after doxycycline treatment in selected patients: a cohort study.Basic and clinical andrology · 2025Article
- Analysis of the burden of disease for male infertility globally and in China from 1990 to 2021.Translational andrology and urology · 2025Article
- From Inflammation to Infertility: How Oxidative Stress and Infections Disrupt Male Reproductive Health.Metabolites · 2025Review
- The consequences of climate change and male reproductive health: A review of the possible impact and mechanisms.Biochemistry and biophysics reports · 2025Review
- Prevalence of HSV-1/HSV-2 and CMV Infections in Infertile Men and Their Impact on Sperm Parameters: A Cross-Sectional Study in Iran.Health science reports · 2025Article
- The possible pathogenic mechanisms of microorganisms in infertility: a narrative review.Archives of microbiology · 2025Review
- Agent-based modelling reveals feedback loops and non-linearity between mating system evolution and disease dynamics.PloS one · 2025Article
- HPV and co-infections: impacts on semen inflammation, oxidative stress, and sperm quality.Frontiers in cellular and infection microbiology · 2025Article
- Parental health at preconception and gestational age at birth: evidence from a population-based cohort using double machine learning.World journal of pediatric surgery · 2025Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sexually transmitted diseases (STDs) are caused by several pathogens, including bacteria, viruses and protozoa, and can induce male infertility through multiple pathophysiological mechanisms. Additionally, horizontal transmission of STD pathogens to sexual partners or vertical transmission to fetuses and neonates is possible. Chlamydia trachomatis, Ureaplasma spp., human papillomavirus, hepatitis B and hepatitis C viruses, HIV-1 and human cytomegalovirus have all been detected in semen from symptomatic and asymptomatic men with testicular, accessory gland and urethral infections. These pathogens are associated with poor sperm quality and decreased sperm concentration and motility. However, the effects of these STD agents on semen quality are unclear, as are the effects of herpes simplex virus type 1 and type 2, Neisseria gonorrhoeae, Mycoplasma spp., Treponema pallidum and Trichomonas vaginalis, because few studies have evaluated the influence of these pathogens on male infertility. Chronic or inadequately treated infections seem to be more relevant to infertility than acute infections are, although in many cases the exact aetiological agents remain unknown.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.