Evidence map›Paper›PMID 25330750›Full record

ReviewJournal of surgical oncology2015

Targeted therapy in sarcomas other than GIST tumors.

Douglas Sborov, James L Chen

Abstract readReview
In one paragraph

Review in Journal of surgical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Managing sarcoma: where have we come from and where are we going?Therapeutic advances in medical oncology · 2017
    Review
  7. Article
  8. Survival After Resection of Gastrointestinal Stromal Tumor and Sarcoma Liver Metastases in 146 Patients.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Douglas SborovDepartment of Internal Medicine, The Ohio State University, Columbus, Ohio.
James L Chen

Funding

Training Hematology and Oncology Fellows in Clinical ResearchT32CA165998 · NCI · OHIO STATE UNIVERSITY · PI CLINTON, STEVEN K, GARZON, RAMIRO · 2012 to 2016
$944k
NCI NIH HHS T32 CA165998
6 · The paper itself

Abstract

Non-GIST soft tissue sarcomas are a heterogeneous grouping of mesenchymal tumors that comprise less than 1% of adult malignancies. Treatment continues to be based on cytotoxic chemotherapy regimens. However, characterization of the molecular pathway deregulations that drive these tumors has led to the emergence of more customized treatment options. In this review, we focus on the multitude of molecular inhibitors targeting angiogenesis and cell cycle pathways being tested in clinical trials.

Indexed as

Angiogenesis InhibitorsAntineoplastic AgentsCell CycleGastrointestinal NeoplasmsGastrointestinal Stromal TumorsHumansMolecular Targeted TherapySarcomaAngiogenesis InhibitorsAntineoplastic Agentsangiogenesis inhibitorscell cycle inhibitorsnon-GIST soft tissue sarcomatargeted therapy

Identifiers

PMID25330750
PMCPMC4436975

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.