Observational studyJournal of medical toxicology : official journal of the American College of Medical Toxicology2015
Real-time mobile detection of drug use with wearable biosensors: a pilot study.
Observational study in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 100 citations in OpenAlex.
- A wearable acoustofluidic patch for rapid reversal of opioid overdose.Nature communications · 2026Article
- Detecting Ethanol Intoxication and Impairment Using Wearable Biosensors.Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences · 2026Article
- Artificial Intelligence Applications in Emergency Toxicology: Advancements and Challenges.Journal of medical Internet research · 2025Review
- Article
- Monitoring Substance Use with Fitbit Biosignals: A Case Study on Training Deep Learning Models Using Ecological Momentary Assessments and Passive Sensing.AI (Basel, Switzerland) · 2024Article
- Association of Drugs for Sale on the Internet and Official Health Indicators: Darknet Parsing and Correlational Study.JMIR formative research · 2024Article
- An autonomous implantable device for the prevention of death from opioid overdose.Science advances · 2024Article
- An Autonomous Implantable Device for the Prevention of Death from Opioid Overdose.bioRxiv : the preprint server for biology · 2024Article
- A Wearable Device Towards Automatic Detection and Treatment of Opioid Overdose.IEEE transactions on biomedical circuits and systems · 2024Article
- Advancing biological investigations using portable sensors for detection of sensitive samples.Heliyon · 2023Review
- Opioid Overdose Detection in a Murine Model Using a Custom-Designed Photoplethysmography Device.Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research · 2023Article
- Discriminating cocaine use from other sympathomimetics using wearable electrocardiographic (ECG) sensors.Drug and alcohol dependence · 2023Article
- Wearable Sensor and Mobile App-Based mHealth Approach for Investigating Substance Use and Related Factors in Daily Life: Protocol for an Ecological Momentary Assessment Study.JMIR research protocols · 2023Article
- Overdose Detection Technologies to Reduce Solitary Overdose Deaths: A Literature Review.International journal of environmental research and public health · 2023Review
- Challenges and future trends in wearable closed-loop neuromodulation to efficiently treat methamphetamine addiction.Frontiers in psychiatry · 2023Review
- Identifying Biomarkers for Accurate Detection of Stress.Sensors (Basel, Switzerland) · 2022Article
- Leveraging Accelerometry as a Prognostic Indicator for Increase in Opioid Withdrawal Symptoms.Biosensors · 2022Article
- The evaluation of the role of technology in the pathways to comorbidity care implementation project to improve management of comorbid substance use and mental disorders.Journal of multimorbidity and comorbidity · 2022Article
- Paper and thread as media for the frugal detection of urinary tract infections (UTIs).Analytical and bioanalytical chemistry · 2022Review
- Willingness to use a wearable device capable of detecting and reversing overdose among people who use opioids in Philadelphia.Harm reduction journal · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
While reliable detection of illicit drug use is paramount to the field of addiction, current methods involving self-report and urine drug screens have substantial limitations that hinder their utility. Wearable biosensors may fill a void by providing valuable objective data regarding the timing and contexts of drug use. This is a preliminary observational study of four emergency department patients receiving parenteral opioids and one individual using cocaine in a natural environment. A portable biosensor was placed on the inner wrist of each subject, to continuously measure electrodermal activity (EDA), skin temperature, and acceleration. Data were continuously recorded for at least 5 min prior to drug administration, during administration, and for at least 30 min afterward. Overall trends in biophysiometric parameters were assessed. Injection of opioids and cocaine use were associated with rises in EDA. Cocaine injection was also associated with a decrease in skin temperature. Opioid tolerance appeared to be associated with a blunted physiologic response as measured by the biosensor. Laterality may be an important factor, as magnitude of response varied between dominant and nondominant wrists in a single patient with bilateral wrist measurements. Changes in EDA and skin temperature are temporally associated with intravenous administration of opioids and cocaine; the intensity of response, however, may vary depending on history and extent of prior use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.