Dementia: Does vitamin D modulate cognition?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Low serum vitamin D levels increase the mortality of cardiovascular disease in older adults: A dose-response meta-analysis of prospective studies.Medicine · 2019
   Pooled it
2. Vitamin D deficiency is associated with increased risk of Alzheimer's disease and dementia: evidence from meta-analysis.Nutrition journal · 2015
   Pooled it
3. Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial.Age and ageing · 2025
   Trial
4. Improving Recovery and Outcomes Every Day After the ICU (IMPROVE): A Randomized Controlled Trial.Critical care medicine · 2025
   Trial
5. Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial.JAMA network open · 2023
   Trial
6. Combining exercise with cognitive training and vitamin DGeroScience · 2023
   Trial
7. SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment.BMC geriatrics · 2018
   Trial
8. Metabolic signatures, vitamin D, and red cell distribution width in dementia risk: UK Biobank insights.GeroScience · 2026
   Article
9. Vitamin D deficiency and disease conditions relevant to: Orthopaedic translation.Journal of orthopaedic translation · 2026
   Review
10. Long-term residential sunlight exposure associated with cognitive function among adults residing in Finland.Scientific reports · 2022
    Article
11. Editorial: Nutrition and Dementia.The journal of nutrition, health & aging · 2021
    Article
12. Editorial: Vitamin D: Does the Emperor Have No Clothes?The journal of nutrition, health & aging · 2019
    Article
13. Patients and agents - or why we need a different narrative: a philosophical analysis.Philosophy, ethics, and humanities in medicine : PEHM · 2018
    Article
14. Role of Pro-Inflammatory Cytokines and Vitamin D in Probable Alzheimer's Disease with Depression.Aging and disease · 2017
    Article
15. Are low levels of 25(OH) vitamin D and testosterone clinically relevant in men with paraplegia?The journal of spinal cord medicine · 2016
    Article
16. High-dose Vitamin D Supplementation and Improvement in Cognitive Abilities, Insomnia, and Daytime Sleepiness in Adolescent Girls.Basic and clinical neuroscience
    Article

Corrections and comments

• Comment on
  Vitamin D and the risk of dementia and Alzheimer disease.2014
• Comment on
  Serum 25-hydroxyvitamin D and cognitive decline in the very old: the Newcastle 85+ Study.2015

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as