Evidence map›Paper›PMID 25329769›Full record

ArticleJournal of the American Chemical Society2014

Shining light on the dark side of imaging: excited state absorption enhancement of a bis-styryl BODIPY photoacoustic contrast agent.

Mathieu Frenette, Maryam Hatamimoslehabadi, Stephanie Bellinger-Buckley, Samir Laoui, Jeffrey La, Seema Bag, Srivalleesha Mallidi, Tayyaba Hasan, Brett Bouma, Chandra Yelleswarapu and 1 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mathieu FrenetteDepartment of Chemistry and ‡Department of Physics, University of Massachusetts Boston , 100 Morrissey Boulevard, Boston, Massachusetts 02125, United States.
Maryam Hatamimoslehabadi
Stephanie Bellinger-Buckley
Samir Laoui
Jeffrey La
Seema Bag
Srivalleesha Mallidi
Tayyaba Hasan
Brett Bouma
Chandra Yelleswarapu
Jonathan Rochford

Funding

UMass Boston-DF/HCC U54 Partnership (2 of 2)U54CA156734 · NCI · UNIVERSITY OF MASSACHUSETTS BOSTON · PI ADAN COLON-CARMONA, Jill A. Macoska · 2010 to 2026
$24.9M
Targeted Photoactivable Nanocells: Image-based Drug Delivery and Dosimetry in GBMR01CA156177 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HASAN, TAYYABA, POGUE, BRIAN WILLIAM · 2011 to 2015
$2.5M
VisualSonics Photoacoustic and Ultrasound Imaging SystemS10OD012326 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI HASAN, TAYYABA · 2012 to 2012
$912k
Glioblastoma PDT Design: Nanoagent Uptake and Tumor Oxygenation based dosimetryF32CA165881 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI MALLIDI, SRIVALLEESHA · 2012 to 2014
$163k
NCI NIH HHS 5R01CA156177NCI NIH HHS F32 CA165881NCI NIH HHS F32CA165881NCI NIH HHS R01 CA156177NCI NIH HHS U54 CA156734NCI NIH HHS U54CA156734NIH HHS S10 OD012326NIH HHS S10OD012326
6 · The paper itself

Abstract

A first approach toward understanding the targeted design of molecular photoacoustic contrast agents (MPACs) is presented. Optical and photoacoustic Z-scan spectroscopy was used to identify how nonlinear (excited-state) absorption contributes to enhancing the photoacoustic emission of the curcuminBF2 and bis-styryl (MeOPh)2BODIPY dyes relative to Cy3.

Indexed as

Absorption, PhysicochemicalBoron CompoundsColoring AgentsContrast MediaDrug DesignOptical ImagingPhotoacoustic Techniques4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsColoring AgentsContrast Media

Identifiers

PMID25329769
PMCPMC4235371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.