Evidence map›Paper›PMID 25329539›Full record

ArticlePloS one2014

Highly efficient and enzymatic regioselective undecylenoylation of gastrodin in 2-methyltetrahydrofuran-containing systems.

Rongling Yang, Xueming Liu, Zhiyi Chen, Chunying Yang, Yaosheng Lin, Siyuan Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rongling YangSericulture and Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Xueming LiuSericulture and Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Zhiyi ChenSericulture and Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Chunying YangSericulture and Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Yaosheng LinSericulture and Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Siyuan WangSericulture and Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Guangdong Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly efficient and regioselective acylation of pharmacologically interesting gastrodin with vinyl undecylenic acid has been firstly performed through an enzymatic approach. The highest catalytic activity and regioselectivity towards the acylation of 7'-hydroxyl of gastrodin was obtained with Pseudomonas cepacia lipase. In addition, it was observed the lipase displayed higher activity in the eco-friendly solvent 2-methyltetrahydrofuran-containing systems than in other organic solvents. In the co-solvent mixture of tetrahydrofuran and 2-methyltetrahydrofuran (3/1, v/v), the reaction rate was 60.6 mM/h, substrate conversion exceeded 99%, and 7'-regioselectivity was 93%. It was also interesting that the lipase-catalyzed acylation couldn't be influenced by the benzylic alcohol in gastrodin. However, pseudomonas cepacia lipase displayed different regioselectivity towards gastrodin and arbutin.

Indexed as

AcylationBenzyl AlcoholsBurkholderia cepaciaEnzyme StabilityFuransGlucosidesKineticsLipaseSolventsStereoisomerismSubstrate SpecificityUndecylenic Acids2-methyltetrahydrofuranBenzyl AlcoholsFuransgastrodinGlucosidesLipaseSolventsundecylenic acidUndecylenic Acids

Identifiers

PMID25329539
PMCPMC4199662
OpenAlexW2081106407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.