Evidence map›Paper›PMID 25328667›Full record

ArticleClinical and translational allergy2014

Dietary elimination of children with food protein induced gastrointestinal allergy - micronutrient adequacy with and without a hypoallergenic formula?

Rosan Meyer, Claire De Koker, Robert Dziubak, Heather Godwin, Gloria Dominguez-Ortega, Neil Shah

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational allergy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Zinc bioaccessibility of foodstuffs afterFood & nutrition research · 2025
    Article
  7. Article
  8. Nutritional risks in children with food allergy.Turkish journal of medical sciences · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Observational
  18. Review
  19. Article
  20. Diets for diagnosis and management of food allergy: The role of the dietitian in eosinophilic esophagitis in adults and children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Rosan MeyerGastroenterology Department, Great Ormond Street Hospital for Children NHS foundation Trust, London, UK.
Claire De KokerGastroenterology Department, Great Ormond Street Hospital for Children NHS foundation Trust, London, UK ; Department of Nutrition and Dietetics, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
Robert DziubakGastroenterology Department, Great Ormond Street Hospital for Children NHS foundation Trust, London, UK.
Heather GodwinGastroenterology Department, Great Ormond Street Hospital for Children NHS foundation Trust, London, UK.
Gloria Dominguez-OrtegaGastroenterology and Nutrition Department, Niño Jesús Children University Hospital, Madrid, Spain.
Neil ShahGastroenterology Department, Great Ormond Street Hospital for Children NHS foundation Trust, London, UK ; Katholic University Hospital, TARGID, Leuven, Belgium.
Great Ormond Street Hospital for Children NHS Foundation Trust · GBHospital Infantil Universitario Niño Jesús · ESKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe cornerstone for management of Food protein-induced gastrointestinal allergy (FPGIA) is dietary exclusion; however the micronutrient intake of this population has been poorly studied. We set out to determine the dietary intake of children on an elimination diet for this food allergy and hypothesised that the type of elimination diet and the presence of a hypoallergenic formula (HF) significantly impacts on micronutrient intake.

methodA prospective observational study was conducted on children diagnosed with FPIGA on an exclusion diet who completed a 3 day semi-quantitative food diary 4 weeks after commencing the diet. Nutritional intake where HF was used was compared to those without HF, with or without a vitamin and mineral supplement (VMS).

resultsOne-hundred-and-five food diaries were included in the data analysis: 70 boys (66.7%) with median age of 21.8 months [IQR: 10 - 67.7]. Fifty-three children (50.5%) consumed a HF and the volume of consumption was correlated to micronutrient intake. Significantly (p <0.05) more children reached their micronutrient requirements if a HF was consumed. In those without a HF, some continued not to achieve requirements in particular for vitamin D and zinc, in spite of VMS.

conclusionThis study points towards the important micronutrient contribution of a HF in children with FPIGA. Children, who are not on a HF and without a VMS, are at increased risk of low intakes in particular vitamin D and zinc. Further studies need to be performed, to assess whether dietary intake translates into actual biological deficiencies.

Identifiers

PMID25328667
PMCPMC4201676
OpenAlexW2100882363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.