Evidence map›Paper›PMID 25328529›Full record

ArticleObstetrics and gynecology international2014

Risk Factors for Preterm Birth among HIV-Infected Tanzanian Women: A Prospective Study.

Rachel M Zack, Jenna Golan, Said Aboud, Gernard Msamanga, Donna Spiegelman, Wafaie Fawzi

Abstract read
In one paragraph

Article in Obstetrics and gynecology international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Intestinal Barrier Dysfunction and Microbial Translocation in Human Immunodeficiency Virus-Infected Pregnant Women Are Associated With Preterm Birth.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  9. Article
  10. Article
  11. Article
  12. Immune activation and paediatric HIV-1 disease outcome.Current opinion in HIV and AIDS · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachel M ZackDepartment of Epidemiology, Harvard School of Public Health, 1633 Tremont Street, Boston, MA 02115, USA.
Jenna GolanDepartment of Nutrition, Harvard School of Public Health, Boston, MA, USA.
Said AboudDepartment of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Gernard MsamangaDepartment of Community Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Donna SpiegelmanDepartment of Epidemiology, Harvard School of Public Health, 1633 Tremont Street, Boston, MA 02115, USA ; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA ; Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA.
Wafaie FawziDepartment of Epidemiology, Harvard School of Public Health, 1633 Tremont Street, Boston, MA 02115, USA ; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA ; Department of Global Health and Population, Harvard School of Public Health, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Premature delivery, a significant cause of child mortality and morbidity worldwide, is particularly prevalent in the developing world. As HIV is highly prevalent in much of sub-Saharan Africa, it is important to determine risk factors for prematurity among HIV-positive pregnancies. The aims of this study were to identify risk factors of preterm (<37 weeks) and very preterm (<34 weeks) birth among a cohort of 927 HIV positive women living in Dar es Salaam, Tanzania, who enrolled in the Tanzania Vitamin and HIV Infection Trial between 1995 and 1997. Multivariable relative risk regression models were used to determine the association of potential maternal risk factors with premature and very premature delivery. High rates of preterm (24%) and very preterm birth (9%) were found. Risk factors (adjusted RR (95% CI)) for preterm birth were mother <20 years (1.46 (1.10, 1.95)), maternal illiteracy (1.54 (1.10, 2.16)), malaria (1.42 (1.11, 1.81)), Entamoeba coli (1.49 (1.04, 2.15)), no or low pregnancy weight gain, and HIV disease stage ≥2 (1.41 (1.12, 1.50)). Interventions to reduce pregnancies in women under 20, prevent and treat malaria, reduce Entamoeba coli infection, and promote weight gain in pregnant women may have a protective effect on prematurity.

Identifiers

PMID25328529
PMCPMC4195401

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.