Evidence map›Paper›PMID 25328397›Full record

ArticleTherapeutics and clinical risk management2014

Prevalence of conventional risk factors and lipid profiles in patients with acute coronary syndrome and significant coronary disease.

Héctor González-Pacheco, Jesús Vargas-Barrón, Maite Vallejo, Yigal Piña-Reyna, Alfredo Altamirano-Castillo, Pedro Sánchez-Tapia, Carlos Martínez-Sánchez

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

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  11. Comorbid conditions in individuals assessed by SPECT: Study of a reference cardiology center in Mexico City.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
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  13. Elevated DNA Damage, Oxidative Stress, and Impaired Response Defense System Inflicted in Patients With Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Héctor González-PachecoCoronary Care Unit, National Institute of Cardiology in Mexico City, Mexico City, Mexico.
Jesús Vargas-BarrónDepartment of Clinical Research, National Institute of Cardiology in Mexico City, Mexico City, Mexico.
Maite VallejoDepartment of Clinical Research, National Institute of Cardiology in Mexico City, Mexico City, Mexico.
Yigal Piña-ReynaCatheterization Laboratory, National Institute of Cardiology in Mexico City, Mexico City, Mexico.
Alfredo Altamirano-CastilloCoronary Care Unit, National Institute of Cardiology in Mexico City, Mexico City, Mexico.
Pedro Sánchez-TapiaCoronary Care Unit, National Institute of Cardiology in Mexico City, Mexico City, Mexico.
Carlos Martínez-SánchezCoronary Care Unit, National Institute of Cardiology in Mexico City, Mexico City, Mexico.
Instituto Nacional de Cardiología · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong patients with coronary artery disease (CAD), 80%-90% present at least one conventional risk factor. On the other hand, lipid profile modification after a cardiovascular event related to acute coronary syndrome (ACS) has been recognized. The prevalence of conventional risk factors and the lipid profile at the time of admission in patients with ACS and significant CAD (stenosis ≥50%) determined through coronary angiography is not well described.

methodsWe studied 3,447 patients with a diagnosis of ACS and significant CAD with stenosis ≥50%, as shown o n angiography. We recorded the presence of conventional risk factors, including smoking, hypertension, dyslipidemia, and diabetes. In addition, we analyzed the lipid profiles within the first 24 hours of admission. We analyzed the studied population and compared findings according to sex.

resultsMost patients (81.7%) were male. ST-elevation myocardial infarction was present in 51.3% of patients, and non-ST-elevation acute coronary syndrome was present in 48.7%. The most frequent risk factor was smoking, which was present in 68% of patients, followed by hypertension (57.8%), dyslipidemia (47.5%), and diabetes (37.7%). In women, the most frequent risk factors were hypertension, diabetes, and dyslipidemia, whereas in men, smoking was the most frequent. We identified at least one risk factor in 95.7% of all patients, two or three risk factors in 62%, and four risk factors in 8.6% of patients. The lipid profile analysis revealed that 85.1% of patients had some type of dyslipidemia, and the most frequent was low levels of high-density lipoprotein cholesterol (68.6% of cases).

conclusionWe found at least one conventional risk factor in 95.7% of patients with ACS and significant CAD. The lipid profile analysis revealed that two thirds of cases had low high-density lipoprotein cholesterol levels.

Indexed as

acute coronary syndromeconventional risk factorsHDL-CNSTEACSSTEMI

Identifiers

PMID25328397
PMCPMC4199556
OpenAlexW1993230446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.