ArticleTherapeutics and clinical risk management2014
Clinical management and therapeutic outcome of infertile couples in southeast Nigeria.
Article in Therapeutics and clinical risk management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- Molecular prevalence of Chlamydia trachomatis infection among women attending gynaecological clinic for infertility evaluation.BMC women's health · 2025Article
- Tertiary care for infertile couples: aetiological diagnoses and conventional treatment outcomes in Kisangani, Democratic Republic of the Congo.Contraception and reproductive medicine · 2023Article
- Pharmacotherapy for Infertility in Ghana: A Prospective Study on Prescription Patterns and Treatment Outcomes among Women undergoing Fertility Treatment.Current therapeutic research, clinical and experimental · 2023Article
- IVF and other ART in low- and middle-income countries: a systematic landscape analysis.Human reproduction update · 2021Review
- Perception of Key Ethical Issues in Assisted Reproductive Technology (ART) by Providers and Clients in Nigeria.International journal of women's health · 2021Article
- Infertility and associated factors in three hospitals in Douala, Cameroon: a cross-sectional study.African health sciences · 2020Article
- Use and pattern of previous care received by infertile Nigerian women.Fertility research and practice · 2019Article
- Availability, effectiveness and safety of ART in sub-Saharan Africa: a systematic review.Human reproduction open · 2018Review
- Prevalence and Etiological Pattern of Infertility in Women Presenting to a Gynecology Clinic in a Secondary Health Facility, South-South, Nigeria: A Cross-Sectional Study.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfertility is highly prevalent in Nigeria and most infertile couples in southeast Nigeria are offered conventional forms of treatment, which consist mainly of ovulation induction and tubal surgery, due to limited availability and high cost of endoscopic and assisted reproductive technologies like laparoscopy and in vitro fertilization. The aim of this study was to determine the prevalence of infertility, outcome of infertility investigation, and the treatment outcome of infertile couples following therapeutic interventions in southeast Nigeria over a 12-month period.
methodsThis was a prospective cross-sectional study of 218 consecutive infertile couples presenting for infertility management at the infertility clinics of two tertiary health institutions in Enugu, southeast Nigeria. Infertility investigations were carried out on these couples using the available conventional diagnostic facilities. Following the results of the investigations/diagnosis, conventional treatment was offered to the couples as appropriate. Data analysis was both descriptive and inferential at 95% confidence level.
resultsThe mean age of the women was 33.5±4.62 (range: 15-49) years. Most (58.3% [n=127]) were nulliparous. The prevalence of infertility was 12.1%. Infertility was primary in 28.4% (n=62) and secondary in 71.6% (n=156). Female etiologic factors were responsible in 32.1% (n=70), male factors in 26.1% (n=57), and a combination of male/female factors in 29.4% (n=64). The etiology was unknown in 12.4% (n=27). Tubal factors 23.8 % (n=52) and ovulation failures 26.1% (n=57) are common female factors implicated. Pregnancy rate following treatment was 16.7% (n=28). Multivariate regression analysis indicates that younger age of ≤30 years, duration of infertility ≤5 years, and female factor infertility were associated with higher pregnancy outcome following treatment.
conclusionThe prevalence of infertility is high and pregnancy rate following conventional treatment is poor. There is a need to improve facilities for managing infertility as well as making artificial reproductive techniques readily available, accessible, and affordable.
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