Evidence map›Paper›PMID 25328036›Full record

ArticleRespirology (Carlton, Vic.)2015

Menthol cigarette smoking in the COPDGene cohort: relationship with COPD, comorbidities and CT metrics.

Seoung Ju Park, Marilyn G Foreman, Dawn L Demeo, Surya P Bhatt, Nadia N Hansel, Robert A Wise, Xavier Soler, Russell P Bowler

Open access · greenAbstract read
In one paragraph

Article in Respirology (Carlton, Vic.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung.International journal of environmental research and public health · 2019
    Article
  5. Flavorings in Tobacco Products Induce Endothelial Cell Dysfunction.Arteriosclerosis, thrombosis, and vascular biology · 2018
    Article
  6. Article
  7. Article
  8. Why We Must Continue to Investigate Menthol's Role in the African American Smoking Paradox.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 2 countries.

Seoung Ju ParkDepartment of Medicine, National Jewish Health, Denver, Colorado, USA; Department of Internal Medicine and Research Institute of Clinical Medicine-Biomedical Research Institute of Chonbuk National University Hospital, Chonbuk National University, Jeonju, South Korea.
Marilyn G Foreman
Dawn L Demeo
Surya P Bhatt
Nadia N Hansel
Robert A Wise
Xavier Soler
Russell P Bowler
Harvard University · USJohns Hopkins Medicine · USJohns Hopkins University · USMorehouse School of Medicine · USNational Jewish Health · USUniversity of Alabama at Birmingham · USUniversity of California System · USUniversity of Colorado Denver · US

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9M
Systems Biology, Bioinformatics, and BiostatisticsP01HL105339 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2011 to 2015
$12.2M
Genetic Analysis of Susceptibility to COPD ExacerbationsK01HL092601 · NHLBI · MOREHOUSE SCHOOL OF MEDICINE · PI FOREMAN, MARILYN G. · 2008 to 2012
$711k
NHLBI NIH HHS K01 HL092601NHLBI NIH HHS P01 HL105339NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NIMHD NIH HHS S21 MD000101
6 · The paper itself

Abstract

BACKGROUND AND

objectiveMenthol cigarettes contain higher levels of menthol to produce a characteristic mint flavour and cooling sensation. Compared with non-menthol cigarettes, little information exists on the effects of menthol cigarette smoking on clinical and radiological characteristics of chronic obstructive pulmonary disease (COPD). The main objective of the present study was to examine associations between menthol cigarette use and the risk of COPD and its characteristics, such as exacerbation, comorbidities and computed tomography (CT) abnormalities.

methodsWe analysed the data from 5699 current smokers in the COPDGene cohort to evaluate whether lung function, comorbidities, exacerbations and CT parameters were different between menthol and non-menthol cigarette smokers.

resultsThere were 3758 (65.9%) who reported use of menthol cigarettes. Multivariable regression analysis revealed that younger age, female gender and African-American ethnicity were significantly associated with smoking of menthol cigarettes. No significant associations were found between menthol cigarette use and COPD, major CT findings or comorbidities, such as cardiovascular disease, congestive heart failure, peripheral vascular disease, cerebrovascular disease, hypertension, diabetes, gastro-oesophageal reflux and osteoporosis; however, menthol cigarette smokers were more likely to experience a severe exacerbation of COPD during longitudinal follow-up (odds ratio 1.29; 95% confidence interval: 1.01-1.54) compared with the non-menthol cigarette smokers.

conclusionsThese results confirm that menthol cigarettes are not safer than traditional cigarettes and suggest that menthol cigarette smokers may have more frequent severe exacerbations than non-menthol cigarette smokers.

Indexed as

MentholPulmonary Disease, Chronic ObstructiveSmokingTobacco ProductsAdultAgedAge FactorsBlack or African AmericanComorbidityDisease ProgressionFemaleHumansLongitudinal StudiesMaleMiddle AgedOdds RatioMentholchronic obstructive pulmonary diseasecomputed tomographyexacerbationmentholsmoking

Identifiers

PMID25328036
PMCPMC4415502
OpenAlexW1843825953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.