Evidence map›Paper›PMID 25327825›Full record

ArticleHead & neck2015

Feasibility of transoral robotic-assisted high-resolution microendoscopic imaging of oropharyngeal squamous cell carcinoma.

Alexis Patsias, Laureano Giraldez-Rodriguez, Alexandros D Polydorides, Rebecca Richards-Kortum, Sharmila Anandasabapathy, Timothy Quang, Andrew G Sikora, Brett Miles

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Head & neck, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Cancer Detection Using Hyperspectral Imaging and Evaluation of the Superficial Tumor Margin Variance with Depth.Proceedings of SPIE--the International Society for Optical Engineering · 2019
    Article
  5. Review
  6. Force adaptive robotically assisted endomicroscopy for intraoperative tumour identification.International journal of computer assisted radiology and surgery · 2015
    Article
  7. A novel approach emphasising intra-operative superficial margin enhancement of head-neck tumours with narrow-band imaging in transoral robotic surgery.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alexis PatsiasDepartment of Otolaryngology - Head and Neck Surgery, Head and Neck Cancer Translational Research Program, The Icahn School of Medicine at Mount Sinai, New York, New York.
Laureano Giraldez-RodriguezDepartment of Otolaryngology - Head and Neck Surgery, Head and Neck Cancer Translational Research Program, The Icahn School of Medicine at Mount Sinai, New York, New York.
Alexandros D PolydoridesDepartment of Pathology, The Icahn School of Medicine at Mount Sinai, New York, New York.
Rebecca Richards-KortumDepartment of Bioengineering, Rice University, Houston, Texas.
Sharmila AnandasabapathyDepartment of Gastroenterology, The Icahn School of Medicine at Mount Sinai, New York, New York.
Timothy QuangDepartment of Bioengineering, Rice University, Houston, Texas.
Andrew G SikoraDepartment of Otolaryngology - Head and Neck Surgery, Head and Neck Cancer Translational Research Program, The Icahn School of Medicine at Mount Sinai, New York, New York.
Brett MilesDepartment of Otolaryngology - Head and Neck Surgery, Head and Neck Cancer Translational Research Program, The Icahn School of Medicine at Mount Sinai, New York, New York.
Icahn School of Medicine at Mount Sinai · USRice University · US

Funding

Optical Systems for In Vivo Molecular Imaging of CancerR01CA103830 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI RICHARDS-KORTUM, REBECCA R. · 2004 to 2015
$12.4M
NCI NIH HHS 2R01 CA103830-06A1NCI NIH HHS R01 CA103830
6 · The paper itself

Abstract

backgroundTransoral robotic-assisted oncologic surgery of the head and neck offers promising functional results. Nonetheless, the efficacy of oncologic surgery remains critically dependent on obtaining negative margins. We aimed to integrate a miniaturized high-resolution fiber-optic microendoscope (HRME), which provides real-time histological assessment, with the da Vinci robotic system (Intuitive Surgical, Sunnyvale, CA).

methodsThree patients undergoing transoral robotic surgery (TORS) were prospectively enrolled in this study. Optical imaging of the oropharynx was performed intraoperatively with the robotic-assisted HRME.

resultsAll patients underwent the procedure successfully with no complications. The HRME was successfully integrated with the da Vinci robotic system. Several sites of the oropharynx and associated malignancy were imaged, which correlated with the standard histopathological analysis.

conclusionTransoral robotic-assisted HRME imaging of the oropharynx is a safe and technically feasible approach, providing a real-time histological assessment and may serve as a valuable aid in oncologic surgery.

Indexed as

EndoscopesImage EnhancementRoboticsCarcinoma, Squamous CellFeasibility StudiesFiber Optic TechnologyHumansMicroscopyMouthNatural Orifice Endoscopic SurgeryNeck DissectionOropharyngeal NeoplasmsProspective StudiesSensitivity and SpecificityTreatment Outcomehigh-resolution fiber-optic microendoscope (HRME)microendoscopyoptical imagingoropharynxsquamous cell carcinomatransoral robotic surgery

Identifiers

PMID25327825
PMCPMC4478240
OpenAlexW2079760587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.