ArticleRedox report : communications in free radical research2015
The oxidative stress index increases among patients with hyperemesis gravidarum but not in normal pregnancies.
Article in Redox report : communications in free radical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Investigation of Endoplasmic Reticulum Stress in Pregnant Women with Hyperemesis Gravidarum.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Investigation of Endoplasmic Reticulum Stress in Pregnant Women with Hyperemesis Gravidarum.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Article
- The Association of Phytochemical Index and oxidative balance score with bone Mineral density: a case-control study.Journal of health, population, and nutrition · 2025Article
- Measurement of Oxidative Stress Index (OSI) in Penile Corpora Cavernosa and Peripheral Blood of Peyronie's Disease Patients: A Report of 49 Cases.Metabolites · 2024Article
- Markers of Oxidative Stress in Obstetrics and Gynaecology-A Systematic Literature Review.Antioxidants (Basel, Switzerland) · 2022Review
- Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2019Article
- Can the Thiol/Disulfide Imbalance Be a Predictor of Colchicine Resistance in Familial Mediterranean Fever?Journal of Korean medical science · 2017Article
- Thiol/disulphide homeostasis in pregnant women with Familial Mediterranean fever.Redox report : communications in free radical research · 2016Article
- Dynamic thiol-disulfide homeostasis in hyperemesis gravidarum.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe etiology and pathogenesis of hyperemesis gravidarum (HG) is still undetermined and has been suggested to involve oxidative stress. We aimed to evaluate the status of oxidative stress in HG by measuring the levels of total oxidant status (TOS), total antioxidant status (TAS), and by calculating the oxidative stress index (OSI).
methodsIn a case-control trial, fasting morning blood samples of patients with HG (n = 41) and healthy pregnant women (n = 39) were collected for analysis of serum TOS and TAS values as well as for calculation of OSI according to the formula: OSI = TOS / TAS × 100.
resultsSerum TOS and TAS levels were similar in both groups. However, serum TAS levels were lower among HG patients compared to controls, which resulted in an increase in OSI (P = 0.025). DISCUSSION: The present study supports the role of systemic oxidative stress, reflected by an imbalance between the TOS and TAS, in patients with HG. Our findings distinguish the mechanism underlying oxidative stress to result from reduction of antioxidants rather than an increase in oxidants.
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