Evidence map›Paper›PMID 25327490›Full record

ArticleExpert review of molecular diagnostics2014

Non-coding RNAs as clinical biomarkers for cancer diagnosis and prognosis.

Prasun J Mishra

Open access · greenAbstract readEditorial
In one paragraph

Article in Expert review of molecular diagnostics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Genome-wide long non-coding RNAs identified a panel of novel plasma biomarkers for gastric cancer diagnosis.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019
    Article
  8. Article
  9. Review
  10. Article
  11. Biobanking of Exosomes in the Era of Precision Medicine: Are We There Yet?International journal of molecular sciences · 2015
    Review
  12. Article
  13. Circulating biomarkers for gliomas.Nature reviews. Neurology · 2015
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Prasun J MishraUS Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Laboratory of Cancer Biology and Genetics, Bethesda, MD 20892, USA.
Department of Health and Human Services · US

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Developing more precise diagnostics approaches to predict cancer progression and prognosis is the key to precision medicine. Overwhelming evidence now suggests that small non-coding RNAs such as miRNAs can be useful tools as biomarkers for molecular diagnostics. miRNAs can serve as biomarkers in a variety of diseases, such as neurological disorders, cardiovascular disease, Type II diabetes, cancer and so on. miRNAs can not only be utilized for monitoring treatment but also for patient stratification and hence are promising predictive biomarkers in cancer progression and prognosis, as well as in predicting drug response. This article focuses on some of the recent findings in the field of miRNA biomarkers and discusses its implications for cancer diagnostics and precision medicine.

Indexed as

Biomarkers, TumorHumansNeoplasmsPolymorphism, GeneticPrognosisRNA, UntranslatedBiomarkers, TumorRNA, Untranslatedbiomarkercirculating microRNAsdiagnosticsmicrovesicles or exosomesmiRNAmiRNA polymorphismspharmacogenomicsprecision medicineprognosisvariants

Identifiers

PMID25327490
PMCPMC4209376
OpenAlexW2006847824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.