ArticlePhysics in medicine and biology2014
Simultaneous estimation of bidirectional particle flow and relative flux using MUSIC-OCT: phantom studies.
Article in Physics in medicine and biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Optical coherence tomography angiography measures blood pulsatile waveforms at variable tissue depths.Quantitative imaging in medicine and surgery · 2021Article
- Functional and Structural Reliability of Optic Nerve Head Measurements in Healthy Eyes by Means of Optical Coherence Tomography Angiography.Medicina (Kaunas, Lithuania) · 2020Observational
- Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications.Progress in retinal and eye research · 2017Review
- Optical coherence tomography angiography-based capillary velocimetry.Journal of biomedical optics · 2017Article
- Optical coherence tomography based angiography [Invited].Biomedical optics express · 2017Review
- Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma.PloS one · 2017Article
- Depth-resolved 3D visualization of coronary microvasculature with optical microangiography.Physics in medicine and biology · 2016Article
- Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Glaucoma Using Optical Coherence Tomography-Based Microangiography.Investigative ophthalmology & visual science · 2016Article
- Repeatability and reproducibility of optic nerve head perfusion measurements using optical coherence tomography angiography.Journal of biomedical optics · 2016Article
- Optic nerve head perfusion in normal eyes and eyes with glaucoma using optical coherence tomography-based microangiography.Quantitative imaging in medicine and surgery · 2016Article
- Automated Quantification of Capillary Nonperfusion Using Optical Coherence Tomography Angiography in Diabetic Retinopathy.JAMA ophthalmology · 2016Observational
- Optic Disc Perfusion in Primary Open Angle and Normal Tension Glaucoma Eyes Using Optical Coherence Tomography-Based Microangiography.PloS one · 2016Article
- Review of optical coherence tomography based angiography in neuroscience.Neurophotonics · 2016Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In an optical coherence tomography (OCT) scan from a living tissue, red blood cells (RBCs) are the major source of backscattering signal from moving particles within microcirculatory system. Measuring the concentration and velocity of RBC particles allows assessment of RBC flux and flow, respectively, to assess tissue perfusion and oxygen/nutrition exchange rates within micro-structures. In this paper, we propose utilizing spectral estimation techniques to simultaneously quantify bi-directional particle flow and relative flux by spectral estimation of the received OCT signal from moving particles within capillary tubes embedded in tissue mimicking phantoms. The proposed method can be directly utilized for in vivo quantification of capillaries and microvessels. Compared to the existing methods in the literature that can either quantify flow direction or power, our proposed method allows simultaneous flow (velocity) direction and relative flux (power) estimation.
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Registered trials
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