ArticleIndustrial health2015
Evaluation of oxaliplatin exposure of healthcare workers during heated intraperitoneal perioperative chemotherapy (HIPEC).
Article in Industrial health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Comparative analysis of dermal and inhalation exposures to antineoplastic drugs among workers in the workplaces: a systematic review.BMC public health · 2025Pooled it
- Exposure to Antineoplastic Drugs in Occupational Settings: A Systematic Review of Biological Monitoring Data.International journal of environmental research and public health · 2022Pooled it
- Intraperitoneal Chemotherapy: A Call to Study Reproductive Safety for Healthcare Workers.Annals of surgical oncology · 2025Article
- Dose-Dependent Concentration and Penetration Depth of Cisplatin in Human Lung Tissue During Hyperthermic Exposure.Journal of clinical medicine · 2025Article
- The 2022 PSOGI International Consensus on HIPEC Regimens for Peritoneal Malignancies: HIPEC Technologies.Annals of surgical oncology · 2024Article
- The 2022 PSOGI International Consensus on HIPEC Regimens for Peritoneal Malignancies: Epithelial Ovarian Cancer.Annals of surgical oncology · 2023Article
- Article
- Perception, knowledge and protective practices for surgical staff handling antineoplastic drugs during HIPEC and PIPAC.Pleura and peritoneum · 2022Article
- HIPEC Methodology and Regimens: The Need for an Expert Consensus.Annals of surgical oncology · 2021Review
- Nurses' internal contamination by antineoplastic drugs in hospital centers: a cross-sectional descriptive study.International archives of occupational and environmental health · 2021Observational
- Is the blood of a surgeon performing HIPEC contaminated by irinotecan, its major metabolites and platinum compounds?Pleura and peritoneum · 2021Article
- Trace amounts of irinotecan found in the blood of a surgeon after performing HIPEC: what does it imply?Pleura and peritoneum · 2021Article
- Practice patterns, attitudes, and knowledge among clinicians regarding hyperthermic intraperitoneal chemotherapy and pressurized intraperitoneal aerosol chemotherapy: a national survey by Indian society of peritoneal surface malignancies (ISPSM).Pleura and peritoneum · 2020Article
- Establishing of Peritoneal Surface Malignancy Treatment Program: Background in Ukraine, Patient Selection, Staff Schedule, Perioperative Outcomes of First 28 Patients.Indian journal of surgical oncology · 2020Article
- Occupational safety of pressurized intraperitoneal aerosol chemotherapy (PIPAC).Pleura and peritoneum · 2017Article
- Cisplatin and oxaliplatin surface contamination in intensive care units (ICUs) and hospital wards during attendance of HIPEC patients.International archives of occupational and environmental health · 2016Article
- Safety considerations for Health care Workers involved in Cytoreductive Surgery and Perioperative chemotherapy.Indian journal of surgical oncology · 2016Review
- A critical analysis of the cytoreductive surgery with hyperthermic intraperitoneal chemotherapy combo in the clinical management of advanced gastric cancer: an effective multimodality approach with scope for improvement.Translational gastroenterology and hepatology · 2016Review
- Review
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate air and surface contaminations, and internal contamination of healthcare workers during open-abdomen HIPEC using oxaliplatin. Platinum (Pt) was measured in urine of exposed workers and in multiple air and surface samples. Three successive HIPEC procedures were investigated in each of the two hospitals participating in the study. Analysis of air samples did not detect any oxaliplatin contamination. Heavy contamination of the operating table, the floor at the surgeon's feet, and the surgeon's overshoes were observed. Hand contamination was observed in surgeons using double gloves for intra-abdominal chemotherapy administration, but not in those using three sets of gloves. Pt was not detected in urine samples obtained after HIPEC (<5 ng/L). The main risk of HIPEC is related to direct or indirect skin exposure and can be prevented by correct use of adapted protective equipment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.