Evidence map›Paper›PMID 25327281›Full record

ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2015

Clinical classification of Caroli's disease: an analysis of 30 patients.

Zhong-Xia Wang, Yong-Gang Li, Rui-Lin Wang, Yong-Wu Li, Zhi-Yan Li, Li-Fu Wang, Hui-Ying Yang, Yun Zhu, Yao Wang, Yun-Feng Bai and 3 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 79 citations in OpenAlex.

  1. Observational
  2. Article
  3. A case of pregnancy complicated by caroli disease.BMC pregnancy and childbirth · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Heritable Chronic Cholestatic Liver Diseases: A Review.Journal of clinical and translational hepatology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. AN 84-YEAR-OLD PATIENT WITH CAROLI SYNDROME: WHAT IS THE PROGNOSIS OF THIS CONDITION?European journal of case reports in internal medicine · 2023
    Article
  12. Article
  13. Article
  14. [A case of Caroli's disease confirmed by pathology, atypical symptoms and images].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zhong-Xia WangDepartment of Graduate School, 301 Hospital, Beijing, China; Integrative Medical Centre, 302 Hospital, Beijing, China.
Yong-Gang Li
Rui-Lin Wang
Yong-Wu Li
Zhi-Yan Li
Li-Fu Wang
Hui-Ying Yang
Yun Zhu
Yao Wang
Yun-Feng Bai
Ting-Ting He
Xiao-Feng Zhang
Xiao-He Xiao
Beijing Royal Integrative Medicine Hospital · CN302 Military Hospital of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaroli's disease (CD) is a rare congenital disorder. The early diagnosis of the disease and differentiation of types I and II are of extreme importance to patient survival. This study was designed to review and discuss observations in 30 patients with CD and to clarify the clinical characteristics of the disease.

methodsThe demographic and clinical features, laboratory indicators, imaging findings and pathology results for 30 patients with CD were reviewed retrospectively.

resultsCaroli's disease can occur at any age. The average age of onset in the study cohort was 24 years. Patients who presented with symptoms before the age of 40 years were more likely to develop type II CD. Approximately one-third of patients presented without positive signs at original diagnosis and most of these patients were found to have type I CD on pathology. Anaemia, leucopoenia and thrombocytopoenia were more frequent in patients with type II than type I CD. Magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) examinations were most useful in diagnosing CD.

conclusionsNo typical symptoms, signs or laboratory indicators are able to distinguish CD from other conditions. Both MRCP and CT were most valuable in diagnosis. The two types of CD may be differentiated by age of onset and routine blood tests.

Indexed as

Disease ProgressionAdolescentAdultAgedAge FactorsCaroli DiseaseChildChild, PreschoolCholangiopancreatography, Magnetic ResonanceDiagnostic ImagingFemaleHumansInfantMaleMiddle AgedPrognosis

Identifiers

PMID25327281
PMCPMC4333791
OpenAlexW2028212519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.