ArticleInternational journal of clinical pharmacy2014
Role of clinical pharmacists to prevent drug interactions in cancer outpatients: a single-centre experience.
Article in International journal of clinical pharmacy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Clinical and economic impact of clinical oncology pharmacy in cancer patients receiving injectable anticancer treatments: a systematic review.Journal of cancer research and clinical oncology · 2023Pooled it
- The need for community pharmacists in oncology outpatient care: a systematic review.International journal of clinical pharmacy · 2016Pooled it
- Effect of chemotherapy counseling by pharmacists on quality of life and psychological outcomes of oncology patients in Malaysia: a randomized control trial.Health and quality of life outcomes · 2017Trial
- Assessment of potential drug interactions in rheumatology: a comparative study of decision support software.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Article
- Impact of Clinical Pharmacists' Interventions on Medication Use and Direct Cost Savings in an Inpatient Medical Oncology Setting.Hospital pharmacy · 2026Article
- Development and Psychometric Validation of a Comprehensive Questionnaire to Assess Oncologists' Knowledge of Chemotherapy-Drug Interaction.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- The Role of Pharmacists in Delivering Pharmaceutical Services to Breast Cancer Patients in Clinical and Community Settings: A Scoping Review.Pharmacy (Basel, Switzerland) · 2025Review
- Article
- Early follow-up of outpatients with oral anticancer therapy in the ONCORAL multidisciplinary community-hospital program.The oncologist · 2025Article
- Polypharmacy and drug interactions in older patients with cancer receiving chemotherapy: associated factors.BMC geriatrics · 2024Observational
- Impact of Medication Reconciliation in Oncology Early Phase Studies: A Drug-Drug Interaction Retrospective Study.JCO oncology practice · 2024Article
- Article
- Current practices, gaps, and opportunities on the role of clinical pharmacists in cancer pain management: Perspectives from Nepal.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023Article
- Article
- A Scoping Review on the Relationship between Race/Ethnicity and the Receipt of Supportive Care Medications during Cancer Treatment: Implications for the Clinical Pharmacist.Journal of the American College of Clinical Pharmacy : JACCP · 2022Article
- Real-life drug-drug and herb-drug interactions in outpatients taking oral anticancer drugs: comparison with databases.Journal of cancer research and clinical oncology · 2022Article
- A retrospective evaluation of drug-drug interactions in patients admitted to Internal Medicine Departments in Palestinian Hospitals.SAGE open medicine · 2022Article
- Clinical Pharmacy Services in Ambulatory Oncology: An Environmental Scan of the Canadian Practice Landscape.The Canadian journal of hospital pharmacy · 2022Article
- The Role of Clinical Pharmacy in Preventing Prescribing Errors in the Emergency Department of a Governmental Hospital in Jordan: A Pre-Post Study.Hospital pharmacy · 2021Article
- Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments.International journal of environmental research and public health · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer patients are especially vulnerable to drug interactions, which may alter the efficacy and toxicity of treatment, leading to severe clinical consequences.
objectiveDetermine the incidence of such interactions in patients receiving chemotherapy, as well as to identify the drugs most frequently involved, investigate the influence of the pharmacist's interventions and verify the degree of acceptance of pharmacist's recommendations by the medical team.
settingThe oncology department of a Spanish tertiary hospital.
methodsDuring 3 months, all the drug interactions in the regular combined with treatment for cancer were analysed using two databases, and recommendations were made when clinically significant interactions (CSI) were identified.
main outcome measureIncidence of CSI in oncology outpatients; drugs involved in CSI.
resultsOf the 75 patients included, 31 (41%) presented CSI. Most interactions were among drugs included in the patient's usual treatment. The principal drug groups involved in CSI were cytostatic agents, antiemetics and antidepressants. The hospital pharmacist intervened on 20 occasions (35% of the patients presenting drug interactions). These interventions mainly focused on recommendations to modify or discontinue drug prescriptions, and were followed in 94% of cases.
conclusionThe incidence of drug interactions in cancer patients is high, and they most often involve medications to treat comorbid conditions. The pharmacist, as a member of the multidisciplinary team, can contribute significantly by checking the treatment prescribed and detecting interactions, to reduce medication-related problems and to optimise drug therapy for these patients.
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