ArticleHaematologica2015
Oral administration of a bone morphogenetic protein type I receptor inhibitor prevents the development of anemia of inflammation.
Open access · goldAbstract readLetter
In one paragraph
Article in Haematologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
- Anemia of Inflammation.Advances in experimental medicine and biology · 2025Review
- Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Physiology and Inflammation Driven Pathophysiology of Iron Homeostasis-Mechanistic Insights into Anemia of Inflammation and Its Treatment.Nutrients · 2021Review
- Improving Right Ventricular Function by Increasing BMP Signaling with FK506.American journal of respiratory cell and molecular biology · 2021Article
- Bioactive Lipid O-cyclic phytosphingosine-1-phosphate Promotes Differentiation of Human Embryonic Stem Cells into Cardiomyocytes via ALK3/BMPR Signaling.International journal of molecular sciences · 2021Article
- Ironing out mechanisms of iron homeostasis and disorders of iron deficiency.The Journal of clinical investigation · 2021Review
- Tumor Immune Evasion Induced by Dysregulation of Erythroid Progenitor Cells Development.Cancers · 2021Review
- Regulation of Iron Homeostasis and Related Diseases.Mediators of inflammation · 2020Review
- Article
- Functional Expression of Organic Anion Transporting Polypeptide 1a4 Is Regulated by Transforming Growth Factor-Molecular pharmacology · 2018Article
- Hepcidin Therapeutics.Pharmaceuticals (Basel, Switzerland) · 2018Review
- Bone Morphogenetic Protein-Based Therapeutic Approaches.Cold Spring Harbor perspectives in biology · 2018Review
- Deficiency of the BMP Type I receptor ALK3 partly protects mice from anemia of inflammation.BMC physiology · 2018Article
- The effects of mouse ovarian granulosa cell function and related gene expression by suppressing BMP/Smad signaling pathway.Animal cells and systems · 2018Article
- Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery?The AAPS journal · 2017Review
- Role of hepcidin-ferroportin axis in the pathophysiology, diagnosis, and treatment of anemia of chronic inflammation.Hemodialysis international. International Symposium on Home Hemodialysis · 2017Review
- Anemia of Inflammation: A Review.The Medical clinics of North America · 2017Review
- The SMAD Pathway Is Required for Hepcidin Response During Endoplasmic Reticulum Stress.Endocrinology · 2016Article
- Hepcidin regulation in the anemia of inflammation.Current opinion in hematology · 2016Review
- Targeting BMP signalling in cardiovascular disease and anaemia.Nature reviews. Cardiology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 1 country.
Claire MayeurAnesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA cmayeur@mgh.harvard.edu.
Starsha A KolodziejAnesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Amy WangTherapeutics for Rare and Neglected Diseases (TRND) Program, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD, USA.
Xin XuTherapeutics for Rare and Neglected Diseases (TRND) Program, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD, USA.
Arthur LeeTherapeutics for Rare and Neglected Diseases (TRND) Program, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD, USA.
Paul B YuCardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
John ShenTherapeutics for Rare and Neglected Diseases (TRND) Program, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD, USA.
Kenneth D BlochAnesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Cardiovascular Research Center, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Donald B BlochAnesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
National Institutes of Health · USHarvard University · USMassachusetts General Hospital · USBrigham and Women's Hospital · USNational Center for Advancing Translational Sciences · US
Funding
Novel probes of BMP and TGF-beta signaling and functionR01AR057374 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI YU, PAUL B · 2010 to 2023
$4.5MModulation of Hepcidin-Ferroportin Signaling using Small MoleculesR01DK082971 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BLOCH, DONALD B, PETERSON, RANDALL T · 2009 to 2018
$4.5MNIAMS NIH HHS R01 AR057374NIDDK NIH HHS R01 DK082971NIDDK NIH HHS R01DK082971NINDS NIH HHS 1X01NS070702
Abstract
PubMed holds no abstract for this paper.
Indexed as
Administration, OralAnemiaAnimalsBiological AvailabilityBlotting, WesternBone Morphogenetic Protein Receptors, Type IBone Morphogenetic ProteinsCells, CulturedFemaleInflammationIrritantsMiceMice, Inbred C57BLPyrazolesPyrimidinesReal-Time Polymerase Chain ReactionBone Morphogenetic Protein Receptors, Type IBone Morphogenetic ProteinsIrritantsLDN 193189PyrazolesPyrimidinesRNA, MessengerTurpentineanemia of inflammationBMP inhibitorhepcidin
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.