ArticleApplied and environmental microbiology2015
Nationwide surveillance study of Clostridium difficile in Australian neonatal pigs shows high prevalence and heterogeneity of PCR ribotypes.
Article in Applied and environmental microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 86 citations in OpenAlex.
- One Health genomic insights into environmental and animal reservoirs of community-associatedApplied and environmental microbiology · 2026Article
- Clostridioides difficile as a Zoonotic and Foodborne Pathogen: Reviewing the Global Evidence and South African Data.MicrobiologyOpen · 2026Review
- Article
- The Role ofMicroorganisms · 2025Review
- Clostridioides difficile infections caused by hypervirulent strains: a single-centre real-life study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Whole-genome sequencing of toxigenic Clostridioides difficile reveals multidrug resistance and virulence genes in strains of environmental and animal origin.BMC veterinary research · 2024Article
- Biogeographic distribution and molecular epidemiology ofApplied and environmental microbiology · 2023Article
- Article
- A local-scale One Health genomic surveillance ofMicrobial genomics · 2023Article
- Genomic epidemiology and transmission dynamics of recurrent Clostridioides difficile infection in Western Australia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Article
- Spore-FormingMicrobiology spectrum · 2023Article
- Article
- Clostridioides difficile infection and One Health: an equine perspective.Environmental microbiology · 2022Review
- Survivability ofVeterinary world · 2022Article
- High Prevalence of Clostridium difficile in Home Gardens in Western Australia.Applied and environmental microbiology · 2020Article
- Laboratory-Based Surveillance of Clostridium difficile Infection in Australian Health Care and Community Settings, 2013 to 2018.Journal of clinical microbiology · 2020Article
- A publicly accessible database forMicrobial genomics · 2020Article
- The molecular characters and antibiotic resistance of Clostridioides difficile from economic animals in China.BMC microbiology · 2020Article
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020Review
- Emergence of a non-sporulating secondary phenotype in Clostridium (Clostridioides) difficile ribotype 078 isolated from humans and animals.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clostridium difficile is an important enteric pathogen of humans and the cause of diarrhea and enteritis in neonatal pigs. Outside Australia, prevalence in piglets can be up to 73%, with a single PCR ribotype (RT), 078, predominating. We investigated the prevalence and genotype of C. difficile in Australian pig herds. Rectal swabs (n = 229) were collected from piglets aged <7 days from 21 farms across Australia. Selective culture for C. difficile was performed and isolates characterized by PCR for toxin genes and PCR ribotyping. C. difficile was isolated from 52% of samples by direct culture on chromogenic agar and 67% by enrichment culture (P = 0.001). No association between C. difficile recovery or genotype and diarrheic status of either farm or piglets was found. The majority (87%; 130/154) of isolates were toxigenic. Typing revealed 23 different RTs, several of which are known to cause disease in humans, including RT014, which was isolated most commonly (23%; 36/154). RT078 was not detected. This study shows that colonization of Australian neonatal piglets with C. difficile is widespread in the herds sampled.
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