ArticleDatabase : the journal of biological databases and curation2014
DEOP: a database on osmoprotectants and associated pathways.
Article in Database : the journal of biological databases and curation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Phenogenomics reveals the ecology and evolution of Trichoderma fungi for sustainable agriculture.Nature microbiology · 2026Article
- Microscopy and spatial-metabolomics identify tissue-specific metabolic pathways uncovering salinity and drought tolerance mechanisms in Avicennia marina and Phoenix dactylifera roots.Scientific reports · 2025Article
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- Aromatic amino acid metabolism and active transport regulation are implicated in microbial persistence in fractured shale reservoirs.ISME communications · 2024Article
- Roles of Bacterial Mechanosensitive Channels in Infection and Antibiotic Susceptibility.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Contribution of Exogenous Proline to Abiotic Stresses Tolerance in Plants: A Review.International journal of molecular sciences · 2022Review
- Chemical Profiling, Bioactivity Evaluation and the Discovery of a Novel Biopigment Produced byMolecules (Basel, Switzerland) · 2021Article
- Insight into phenotypic and genotypic differences between vaginalMicrobial genomics · 2021Article
- Untargeted metabolomics as a hypothesis-generation tool in plant protection product discovery: Highlighting the potential of trehalose and glycerol metabolism of fungal conidiospores as novel targets.Metabolomics : Official journal of the Metabolomic Society · 2020Article
- Secondary Metabolites From Halotolerant Plant Growth Promoting Rhizobacteria for Ameliorating Salinity Stress in Plants.Frontiers in microbiology · 2020Review
- Article
- Ecological Conditions and Molecular Determinants Involved inFrontiers in plant science · 2019Review
- Homeostasis of Second Messenger Cyclic-di-AMP Is Critical for Cyanobacterial Fitness and Acclimation to Abiotic Stress.Frontiers in microbiology · 2018Article
- The Genome Sequence of the Wild TomatoFrontiers in plant science · 2018Article
- Beyond Chloride Brines: Variable Metabolomic Responses in the Anaerobic OrganismFrontiers in microbiology · 2018Article
- Growth arrest and a persister state enable resistance to osmotic shock and facilitate dissemination of Vibrio cholerae.The ISME journal · 2017Article
- DESM: portal for microbial knowledge exploration systems.Nucleic acids research · 2016Article
- Article
- Databases for Microbiologists.Journal of bacteriology · 2015Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microorganisms are known to counteract salt stress through salt influx or by the accumulation of osmoprotectants (also called compatible solutes). Understanding the pathways that synthesize and/or breakdown these osmoprotectants is of interest to studies of crops halotolerance and to biotechnology applications that use microbes as cell factories for production of biomass or commercial chemicals. To facilitate the exploration of osmoprotectants, we have developed the first online resource, 'Dragon Explorer of Osmoprotection associated Pathways' (DEOP) that gathers and presents curated information about osmoprotectants, complemented by information about reactions and pathways that use or affect them. A combined total of 141 compounds were confirmed osmoprotectants, which were matched to 1883 reactions and 834 pathways. DEOP can also be used to map genes or microbial genomes to potential osmoprotection-associated pathways, and thus link genes and genomes to other associated osmoprotection information. Moreover, DEOP provides a text-mining utility to search deeper into the scientific literature for supporting evidence or for new associations of osmoprotectants to pathways, reactions, enzymes, genes or organisms. Two case studies are provided to demonstrate the usefulness of DEOP. The system can be accessed at. Database URL: http://www.cbrc.kaust.edu.sa/deop/
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.