ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2015
Anterior resection syndrome--a risk factor analysis.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Efficacy of pelvic floor rehabilitation for bowel dysfunction after anterior resection for colorectal cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Conversations for providers caring for patients with rectal cancer: Comparison of long-term patient-centered outcomes for patients with low rectal cancer facing ostomy or sphincter-sparing surgery.CA: a cancer journal for clinicians · 2016Pooled it
- Physical activity levels after low anterior resection for rectal cancer: one-year follow-up.BMC public health · 2021Trial
- Functional outcomes from a randomized trial of early closure of temporary ileostomy after rectal excision for cancer.The British journal of surgery · 2019Trial
- Trial
- Prevalence of and risk factors for low anterior resection syndrome based on the international consensus definition: a multicenter cross-sectional observational study.Surgery today · 2026Observational
- Low anterior resection syndrome.Annals of gastroenterological surgery · 2023Review
- Low anterior resection syndrome following rectal cancer surgery: are incidence and severity lower with long-term follow-up?Techniques in coloproctology · 2022Article
- The impact of prolonged delay to loop ileostomy closure on postoperative morbidity and hospital stay: A retrospective cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Review
- Prevalence and Risk Factors of Low Anterior Resection Syndrome in Epithelial Ovarian Cancer Surgery.Cureus · 2022Article
- Trajectory of change of low anterior resection syndrome over time after restorative proctectomy for rectal adenocarcinoma.Techniques in coloproctology · 2022Article
- The risk factors of low anterior resection syndrome after colorectal cancer surgery: A retrospective study of 566 patients in a single institution in China.Frontiers in surgery · 2022Article
- The role of colonic motility in low anterior resection syndrome.Frontiers in oncology · 2022Review
- Risk factors for developing anorectal dysfunction after anterior resection.International journal of colorectal disease · 2021Article
- Low anterior resection syndrome: can it be prevented?International journal of colorectal disease · 2021Review
- Effect of Biofeedback Therapy during Temporary Stoma Period in Rectal Cancer Patients: A Prospective Randomized Trial.Journal of clinical medicine · 2021Article
- The Effect of Anastomotic Leakage on the Incidence and Severity of Low Anterior Resection Syndrome in Patients Undergoing Proctectomy: A Propensity Score Matching Analysis.Annals of coloproctology · 2021Article
- Validation of the low anterior resection syndrome score in finnish patients: preliminary results on quality of life in different lars severity groups.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021Article
- Knowledge, attitudes, practices, and related factors of low anterior resection syndrome management among colorectal surgery nurses: a multicenter cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
backgroundEvacuatory dysfunction after distal colorectal resection varies from incontinence to obstructed defaecation and is termed anterior resection syndrome. The aim of this study was to identify risk factors for the development of anterior resection syndrome.
methodsAll anterior resections undertaken at Auckland Hospital from 2002 to 2012 were retrospectively evaluated. An assortment of patient and peri-operative variables were recorded. Cases were stratified by the occurrence of anterior resection syndrome symptoms from 1 to 5 years post-operatively.
resultsA total of 277 patients were identified. Prevalence of anterior resection syndrome decreased progressively from 61 % at 1 year to 43 % at 5 years. Univariate analysis identified anastomotic height, surgeon, pT stage, procedure year and temporary diversion ileostomy as recurring significant correlates (p < 0.05). Logistic regression identified lower anastomotic height (odds ratio (OR) 2.11, 95 % confidence interval (CI) 1.05-4.27; p = 0.04) and obstructive presenting symptoms (OR 6.71, 95 % CI 1.00-44.80; p = 0.05) as independent predictors at 1 and 2 years, respectively. Post-operative chemotherapy was a predictor at 1 year (OR 1.93, 95 % CI 1.04-3.57; p = 0.03). Temporary diverting ileostomy was an independent predictor at 2 (OR 2.49, 95 % CI 1.04-5.95; p = 0.04), 3 (OR 4.17, 95 % CI 1.04-16.78; p = 0.04), 4 (OR 8.05, 95 % CI 1.21-53.6; p = 0.03), and 5 years (OR 49.60, 95 % CI 2.17-1134.71; p = 0.02) after adjusting for anastomotic height.
conclusionsAnastomotic height, post-operative chemotherapy and obstructive presenting symptoms were independent predictors at 1 and 2 years. Temporary diversion ileostomy was an independent predictor for the occurrence of anterior resection syndrome at 2, 3, 4 and 5 years even after correcting for anastomotic height. Prospective assessment is required to facilitate more accurate risk factor analysis.
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