ReviewSeminars in immunopathology2015
Microbiome/microbiota and allergies.
Review in Seminars in immunopathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05215080 (The Tolerance of Organic Formula Milk and Its Fecal Microbiome Characteristic in Infants), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Tolerance of Organic Formula Milk and Its Fecal Microbiome Characteristic in Infants
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- The relationship of prenatal antibiotic exposure and infant antibiotic administration with childhood allergies: a systematic review.BMC pediatrics · 2020Pooled it
- Dysbiosis of gut microbiota with enriched pro-inflammatory species in children with idiopathic short stature: a case-control study.Scientific reports · 2025Article
- Efficacy of probiotics in pediatric atopic dermatitis: A systematic review and meta-analysis.Clinical and translational allergy · 2023Review
- Dynamic changes of the gut microbial colonization in preterm infants with different time points after birth.Frontiers in microbiology · 2023Article
- Assessing the relationship between physical activity and the gut microbiome in a large, population-based sample of Wisconsin adults.PloS one · 2022Article
- Effect of heat-inactivatedBioscience of microbiota, food and health · 2020Article
- Salivary Microbiological and Gingival Health Status Evaluation of Adolescents With Overweight and Obesity: A Cluster Analysis.Frontiers in pediatrics · 2020Article
- A Comparative Review on Microbiota Manipulation: Lessons From Fish, Plants, Livestock, and Human Research.Frontiers in nutrition · 2018Review
- [A preliminary analysis of changes in composition of intestinal microbiota during infancy using polymerase chain reaction-denaturing gradient gel electrophoresis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Regulation of the T Cell Response by CD39.Trends in immunology · 2016Review
- Gut Microbiota Modification: Another Piece in the Puzzle of the Benefits of Physical Exercise in Health?Frontiers in physiology · 2016 · on this mapReview
- Neutral Models of Microbiome Evolution.PLoS computational biology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allergies are characterized by a hypersensitive immune reaction to originally harmless antigens. In recent decades, the incidence of allergic diseases has markedly increased, especially in developed countries. The increase in the frequency of allergic diseases is thought to be primarily due to environmental changes related to a westernized lifestyle, which affects the commensal microbes in the human body. The human gut is the largest organ colonized by bacteria and contains more than 1000 bacterial species, called the "gut microbiota." The recent development of sequencing technology has enabled researchers to genetically investigate and clarify the diversity of all species of commensal microbes. The collective genomes of commensal microbes are together called the "microbiome." Although the detailed mechanisms remain unclear, it has been proposed that the microbiota/microbiome, especially that in the gut, impacts the systemic immunity and metabolism, thus affecting the development of various immunological diseases, including allergies. In this review, we summarize the recent findings regarding the importance of the microbiome/microbiota in the development of allergic diseases and also the results of interventional studies using probiotics or prebiotics to prevent allergies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.