Evidence map›Paper›PMID 25326105›Full record

ReviewSeminars in immunopathology2015

Commensal bacteria and cutaneous immunity.

Satoshi Nakamizo, Gyohei Egawa, Tetsuya Honda, Saeko Nakajima, Yasmine Belkaid, Kenji Kabashima

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 93 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Shared Pathways between Psoriasis and Atopic Dermatitis.Dermatology practical & conceptual · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Skin health and disease · 2025
    Article
  8. Review
  9. Trends in infectious spondylitis from 2000 to 2020.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  10. The inner elbow skin microbiome containsMicrobiome research reports · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. A Journey on the Skin Microbiome: Pitfalls and Opportunities.International journal of molecular sciences · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Satoshi NakamizoDepartment of Dermatology, Kyoto University School of Medicine, 54 Shogoin-Kawahara, Kyoto, 606-8507, Japan.
Gyohei Egawa
Tetsuya Honda
Saeko Nakajima
Yasmine Belkaid
Kenji Kabashima
Kyoto University · JPNational Institutes of Health · US

Funding

Role of the microbiota in immunityZIAAI001115 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BELKAID, YASMINE · 2009 to 2025
$22.4M
6 · The paper itself

Abstract

The skin is the human body's largest organ and is home to a diverse and complex variety of innate and adaptive immune functions that protect against pathogenic invasion. Recent studies have demonstrated that cutaneous commensal bacteria modulated the host immune system. For example, Staphylococcus epidermidis, a skin commensal bacterium, has been demonstrated to induce cutaneous interferon (IFN)-γ- and interleukin (IL)-17A-producing T cells. In addition, cutaneous microbiota changes occur in the chronic inflammatory skin disorders, such as atopic dermatitis, and may influence the activity of skin diseases. In this article, we will review the recent findings related to the interactions of the commensal bacteria with skin homeostasis and discuss the role of the dysbiosis of these bacteria in the pathogenesis of skin diseases.

Indexed as

HumansMicrobiotaSkinSkin DiseasesSymbiosis

Identifiers

PMID25326105
OpenAlexW2021692049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.