ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2014
Obstructive sleep apnea and mandibular advancement splints: occlusal effects and progression of changes associated with a decade of treatment.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 5 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Comparison of side effects of different mandibular advancement devices for patients with obstructive sleep apnea: a systematic review and meta-analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Pooled it
- Dentoskeletal changes of long-term oral appliance treatment in patients with obstructive sleep apnea: A systematic review and meta-analysis.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2025Pooled it
- Effect of mandibular advancement appliance use on oral and periodontal health in patients with OSA: a systematic review.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- A Systematic Review of Oral Modifications Caused by the Prolonged Application of Continuous Positive Airway Pressure (CPAP) and Intraoral Appliances in Patients with Obstructive Sleep Apnea (OSA).BioMed research international · 2024Pooled it
- Oral appliance-generated malocclusion traits during the long-term management of obstructive sleep apnea in adults.The Angle orthodontist · 2022Pooled it
- The comparison of two different mandibular positions for oral appliance therapy in patients with obstructive sleep apnea.Clinical and experimental dental research · 2022Trial
- Frequency and skeletal factors associated with posterior open bite during oral appliance therapy for obstructive sleep apnea: A retrospective study.Sleep & breathing = Schlaf & Atmung · 2026Article
- Retention vs. Stability: A Comparative Study of Thermoplastic Materials for Oral Appliance Therapy.Cureus · 2026Article
- Association of Novel Oral Appliance Use With Heart Rate Variability in Adolescent Athletes.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Bidirectional Relationship Between Dental Diseases and Sleep Disturbances in Pediatric Patients.Clinical and experimental dental research · 2025Review
- Objective adherence to oral appliance therapy in patients with obstructive sleep apnea: a one-year longitudinal analysis.European journal of orthodontics · 2025Article
- Can the use of morning occlusal guides after oral sleep appliances cause root resorption similar to orthodontic jiggling?Sleep & breathing = Schlaf & Atmung · 2025Article
- 3-D changes in tooth position after treatment with mandibular advancement devices -a retrospective study in a non-university setting.BMC oral health · 2025Article
- Predictive factors of therapeutic response according to craniofacial skeletal biotype in patients with sleep apnea syndrome using mandibular advancement devices: a pilot study.The Angle orthodontist · 2024Article
- Review
- A Multicenter Prospective Study on the Use of a Mandibular Advancement Device in the Treatment of Obstructive Sleep Apnea.Dentistry journal · 2023Article
- The role of oral appliance therapy in obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Drug-induced sleep endoscopy improves intervention efficacy among patients treated for obstructive sleep apnea with a mandibular advancement device.Sleep & breathing = Schlaf & Atmung · 2022Article
- A Narrative Review of the Association between Post-Traumatic Stress Disorder and Obstructive Sleep Apnea.Journal of clinical medicine · 2022Review
- Long-term benefits of a new oral appliance on adult snoring: a trend analysis.Multidisciplinary respiratory medicine · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo evaluate the magnitude and progression of dental changes associated with long-term mandibular advancement splint (MAS) treatment of obstructive sleep apnea (OSA).
methodsRetrospective study of adults treated for primary snoring or mild to severe OSA with MAS for a minimum of 8 years. The series of dental casts of patients were analyzed with a digital caliper for changes in overbite, overjet, dental arch crowding and width, and inter-arch relationships. The progression of these changes over time was determined and initial patient and dental characteristics were evaluated as predictors of the observed dental side effects of treatment.
resultsA total of 77 patients (average age at start of treatment: 47.5 ± 10.2 years, 62 males) were included in this study. The average treatment length was 11.1 ± 2.8 years. Over the total treatment interval evaluated there was a significant (p < 0.001) reduction in the overbite (2.3 ± 1.6 mm), overjet (1.9 ± 1.9 mm), and mandibular crowding (1.3 ± 1.8 mm). A corresponding significant (p < 0.001) increase of mandibular intercanine (0.7 ± 1.5 mm) and intermolar (1.1 ± 1.4 mm) width as well as incidence of anterior crossbite and posterior open bite was observed. Overbite and mandibular intermolar distance were observed to decrease less with time, while overjet, mandibular intercanine distance, and lower arch crowding all decreased continuously at a constant rate.
conclusionsAfter an average observation period of over 11 years, clinically significant changes in occlusion were observed and were progressive in nature. Rather than reaching a discernible end-point, the dental side effects of MAS therapy continue with ongoing MAS use. COMMENTARY: A commentary on this article appears in this issue on page 1293.
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