Trial reportSleep2014
Quality-adjusted life-years gain and health status in patients with OSAS after one year of continuous positive airway pressure use.
Trial report in Sleep, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Home-testing devices for diagnosing obstructive sleep apnoea hypopnoea syndrome - a systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- Health utility outcomes in patients undergoing medical management for chronic rhinosinusitis: a prospective multiinstitutional study.International forum of allergy & rhinology · 2015Trial
- Health Preference Measures in Patients with Obstructive Sleep Apnea Syndrome Undergoing Continuous Positive Airway Pressure Therapy: Data from a Randomized Trial.Respiration; international review of thoracic diseasesTrial
- Continuous positive airway pressure usage before and after issue of an urgent product defect correction notice following a global Philips recall.Internal medicine journal · 2026Article
- Impact of Philips device recall on adults with obstructive sleep apnea treated with PAP therapy: Results of a cross-national patient survey.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Exploring the impact of a medical device recall on individuals with obstructive sleep apnea and healthcare providers: a qualitative study.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Level 2 Polysomnography for the Diagnosis of Sleep Disorders: A Health Technology Assessment.Ontario health technology assessment series · 2024Article
- Durable Improvement in Generic and Fibroid-Specific Quality of Life in Women Treated with Transcervical Fibroid Ablation with the Sonata System After Three Years.Journal of gynecologic surgery · 2022Article
- Association of obstructive sleep apnea and opioids use on adverse health outcomes: A population study of health administrative data.PloS one · 2022Article
- Breathing Synchronised Hypoglossal Nerve Stimulation with Inspire for Untreated Severe Obstructive Sleep Apnoea/Hypopnoea Syndrome: A Simulated Cost-Utility Analysis from a National Health Service Perspective.PharmacoEconomics - open · 2021Article
- Perspectives on primary care management of obstructive sleep apnea: a qualitative study of patients and health care providers.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- The cost-effectiveness analysis of drug therapy versus surgery for symptomatic adenoid hypertrophy by a Markov model.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Health utility values for patients with recurrent acute rhinosinusitis undergoing endoscopic sinus surgery: a nested case control study.International forum of allergy & rhinology · 2016Article
- Stem/progenitor cells and obstructive sleep apnea syndrome - new insights for clinical applications.World journal of stem cells · 2016Review
- Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo estimate the health utility score and quality-adjusted life-years (QALY) index of obstructive sleep apnea syndrome (OSAS) in patients over 1 y of continuous positive airway pressure (CPAP) treatment.
designLongitudinal interventional study.
settingThe study was carried out in Sao Paulo Sleep Institute, Brazil. PATIENTS AND
participantsNinety-five patients with OSAS and with apnea-hypopnea index (AHI) > 20 of either sex, body mass index < 40 kg/m(2), and no previous contact with CPAP were included.
interventionsThe participants underwent baseline and titration polysomnographies, clinical evaluation, and ambulatory blood pressure (BP) measurement, completed Short-Form 6 Dimension Health Survey (SF-6D) and Epworth Sleepiness Scale (ESS) questionnaires, and implementation of CPAP. The patients were followed for 1 y. MEASUREMENTS AND
resultsThe mean AHI and age were 57.6 ± 29.2 events/h and 53.3 ± 9.3 y, respectively. One year of CPAP treatment increased the health utility score from 0.611 ± 0.112 to 0.710 ± 0.121 (P < 0.01). Therefore, CPAP resulted in a mean gain of 0.092 QALY/patient. The improvements in utility scores were associated with decreases in the ESS after 1 mo, in systolic BP after 1 y, and in diastolic BP at 6 mo. BP normalization group (≤ 130/85 mmHg) showed higher QALY than that of the non-normalization group (0.10 ± 0.09 versus 0.05 ± 0.10; P = 0.03). One-year ESS score (P = 0.03), diastolic BP reduction P = 0.01) and baseline utility scores (P < 0.01) were significantly associated with QALY gain.
conclusionThis study showed a significant QALY/patient gain after 1 y of regular CPAP use. In addition, BP normalization was associated with higher QALY gain. Thus, utility studies can provide more complete analyses of the total benefits of CPAP treatment in patients with OSAS and should be encouraged.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.