Evidence map›Paper›PMID 25325460›Full record

ArticleSleep2015

Sleep apnea-related risk of motor vehicle accidents is reduced by continuous positive airway pressure: Swedish Traffic Accident Registry data.

Mahssa Karimi, Jan Hedner, Henrike Häbel, Olle Nerman, Ludger Grote

Abstract read
In one paragraph

Article in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Pooled it
  6. Pooled it
  7. Trial
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  11. Review
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  13. Article
  14. Sleep science (Sao Paulo, Brazil) · 2025
    Article
  15. Article
  16. Sleep Disorders and Traffic Accidents: Unveiling the Hidden Risks.The American journal of case reports · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Mahssa KarimiCentre for Sleep and Vigilance Disorder, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jan HednerCentre for Sleep and Vigilance Disorder, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Henrike HäbelDepartment of Mathematical Sciences, Chalmers University of Technology and Department of Mathematical Sciences University of Gothenburg, Gothenburg, Sweden.
Olle NermanDepartment of Mathematical Sciences, Chalmers University of Technology and Department of Mathematical Sciences University of Gothenburg, Gothenburg, Sweden.
Ludger GroteCentre for Sleep and Vigilance Disorder, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesObstructive sleep apnea (OSA) is associated with an increased risk of motor vehicle accidents (MVAs). The rate of MVAs in patients suspected of having OSA was determined and the effect of continuous positive airway pressure (CPAP) was investigated.

designMVA rate in patients referred for OSA was compared to the rate in the general population using data from the Swedish Traffic Accident Registry (STRADA), stratified for age and calendar year. The risk factors for MVAs, using demographic and polygraphy data, and MVA rate before and after CPAP were evaluated in the patient group.

settingClinical sleep laboratory and population based control (n = 635,786). PATIENTS: There were 1,478 patients, male sex 70.4%, mean age 53.6 (12.8) y.

interventionsCPAP. MEASUREMENTS AND

resultsThe number of accidents (n = 74) among patients was compared with the expected number (n = 30) from a control population (STRADA). An increased MVA risk ratio of 2.45 was found among patients compared with controls (P < 0.001). Estimated excess accident risk was most prominent in the elderly patients (65-80 y, seven versus two MVAs). In patients, driving distance (km/y), EDS (Epworth Sleepiness score ≥ 16), short habitual sleep time (≤5 h/night), and use of hypnotics were associated with increased MVA risk (odds ratios 1.2, 2.1, 2.7 and 2.1, all P ≤ 0.03). CPAP use ≥ 4 h/night was associated with a reduction of MVA incidence (7.6 to 2.5 accidents/1,000 drivers/y).

conclusionsThe MVA risk in this large cohort of unselected patients with OSA suggests a need for accurate tools to identify individuals at risk. Sleep apnea severity (e.g., apnea-hypopnea index) failed to identify patients at risk.

Indexed as

Motor VehiclesAccidents, TrafficAdolescentAdultAgedAged, 80 and overAutomobile DrivingCase-Control StudiesCohort StudiesContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedOdds RatioRegistriesCPAPdaytime sleepinessdriving distancerisk factorstraffic accident

Identifiers

PMID25325460
PMCPMC4335527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.