ArticleThe ISME journal2015
Integrating phylogeny, geographic niche partitioning and secondary metabolite synthesis in bloom-forming Planktothrix.
Article in The ISME journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Single-cell genomics, metagenomics, and transcriptomics ofAquatic ecology · 2026Article
- Article
- High Structural Diversity of Aeruginosins in Bloom-Forming Cyanobacteria of the GenusMarine drugs · 2023Article
- Multi-year molecular quantification and 'omics analysis ofFrontiers in microbiology · 2023Article
- Article
- Review
- Article
- Toxic/Bioactive Peptide Synthesis Genes Rearranged by Insertion Sequence Elements Among the Bloom-Forming CyanobacteriaFrontiers in microbiology · 2022Article
- Article
- Isolation and Characterization ofApplied and environmental microbiology · 2021Article
- Physical drivers facilitating a toxigenic cyanobacterial bloom in a major Great Lakes tributary.Limnology and oceanography · 2020Article
- The Architecture of Metabolism Maximizes Biosynthetic Diversity in the Largest Class of Fungi.Molecular biology and evolution · 2020Article
- Toward Disentangling the Multiple Nutritional Constraints Imposed byFrontiers in microbiology · 2020Article
- Taxonomic Novelty and Distinctive Genomic Features of Hot Spring Cyanobacteria.Frontiers in genetics · 2020Article
- Article
- Seasonal dynamics of freshwater pathogens as measured by microarray at Lake Sapanca, a drinking water source in the north-eastern part of Turkey.Environmental monitoring and assessment · 2017Article
- Predicting blooms of toxic cyanobacteria in eutrophic lakes with diverse cyanobacterial communities.Scientific reports · 2017Article
- Evolution of Anabaenopeptin Peptide Structural Variability in the CyanobacteriumFrontiers in microbiology · 2017Article
- Article
- Are Oligotypes Meaningful Ecological and Phylogenetic Units? A Case Study ofFrontiers in microbiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Toxic freshwater cyanobacteria form harmful algal blooms that can cause acute toxicity to humans and livestock. Globally distributed, bloom-forming cyanobacteria Planktothrix either retain or lose the mcy gene cluster (encoding the synthesis of the secondary metabolite hepatotoxin microcystin or MC), resulting in a variable spatial/temporal distribution of (non)toxic genotypes. Despite their importance to human well-being, such genotype diversity is not being mapped at scales relevant to nature. We aimed to reveal the factors influencing the dispersal of those genotypes by analyzing 138 strains (from Europe, Russia, North America and East Africa) for their (i) mcy gene cluster composition, (ii) phylogeny and adaptation to their habitat and (iii) ribosomally and nonribosomally synthesized oligopeptide products. Although all the strains from different species contained at least remnants of the mcy gene cluster, various phylogenetic lineages evolved and adapted to rather specific ecological niches (for example, through pigmentation and gas vesicle protein size). No evidence for an increased abundance of specific peptides in the absence of MC was found. MC and peptide distribution rather depended on phylogeny, ecophysiological adaptation and geographic distance. Together, these findings provide evidence that MC and peptide production are primarily related to speciation processes, while within a phylogenetic lineage the probability that strains differ in peptide composition increases with geographic distance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.