Evidence map›Paper›PMID 25325278›Full record

ArticleEndocrinology and metabolism (Seoul, Korea)2015

Celiac Disease in a Predisposed Subject (HLA-DQ2.5) with Coexisting Graves' Disease.

In Kyoung Hwang, Seon Hye Kim, Unjoo Lee, Sang Ouk Chin, Sang Youl Rhee, Seungjoon Oh, Jeong Taek Woo, Sung Woon Kim, Young Seol Kim, Suk Chon

Abstract read
In one paragraph

Article in Endocrinology and metabolism (Seoul, Korea), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Case Series: Is Celiac Disease Underdiagnosed in Korean Children?The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Article
  2. Review
  3. Underutilization of diagnostic assays for celiac disease in Korea.Journal of clinical laboratory analysis · 2021
    Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

In Kyoung HwangDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Seon Hye KimDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Unjoo LeeDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Sang Ouk ChinDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Sang Youl RheeDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Seungjoon OhDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Jeong Taek WooDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Sung Woon KimDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Young Seol KimDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Suk ChonDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea. imdrjs@khu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease is an intestinal autoimmune disorder, triggered by ingestion of a gluten-containing diet in genetically susceptible individuals. The genetic predisposition is related to human leukocyte antigen (HLA) class II genes, especially HLA-DQ2-positive patients. The prevalence of celiac disease has been estimated to be ~1% in Europe and the USA, but it is rarer and/or underdiagnosed in Asia. We report a case of celiac disease in a predisposed patient, with a HLA-DQ2 heterodimer, and Graves' disease that was treated successfully with a gluten-free diet. A 47-year-old woman complained of persistent chronic diarrhea and weight loss over a 9 month period. Results of all serological tests and stool exams were negative. However, the patient was found to carry the HLA DQ2 heterodimer. Symptoms improved after a gluten-free diet was initiated. The patient has been followed and has suffered no recurrence of symptoms while on the gluten-free diet. An overall diagnosis of celiac disease was made in a genetically predisposed patient (HLA-DQ2 heterodimer) with Graves' disease.

Indexed as

Celiac diseaseGraves' diseaseHLA-DQ2

Identifiers

PMID25325278
PMCPMC4384671

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.