Evidence map›Paper›PMID 25325017›Full record

ReviewFrontiers in cellular and infection microbiology2014

Current status of antisense RNA-mediated gene regulation in Listeria monocytogenes.

Tilman Schultze, Benjamin Izar, Xiaoxing Qing, Gopala K Mannala, Torsten Hain

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Regulation of Heterogenous LexA Expression inInternational journal of molecular sciences · 2022
    Article
  2. RNA-Mediated Control inFrontiers in microbiology · 2021
    Review
  3. Initial Transcriptomic Response and Adaption ofFrontiers in microbiology · 2019
    Article
  4. Review
  5. Article
  6. Article
  7. Signals behindGut microbes
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tilman SchultzeDepartment of Medicine, Institute of Medical Microbiology, Justus-Liebig University Giessen Giessen, Germany.
Benjamin IzarDepartment of Medicine, Massachusetts General Hospital and Harvard Medical School Boston, MA, USA.
Xiaoxing QingDepartment of Medicine, Institute of Medical Microbiology, Justus-Liebig University Giessen Giessen, Germany.
Gopala K MannalaDepartment of Medicine, Institute of Medical Microbiology, Justus-Liebig University Giessen Giessen, Germany.
Torsten HainDepartment of Medicine, Institute of Medical Microbiology, Justus-Liebig University Giessen Giessen, Germany.
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Listeria monocytogenes is a Gram-positive human-pathogen bacterium that served as an experimental model for investigating fundamental processes of adaptive immunity and virulence. Recent novel technologies allowed the identification of several hundred non-coding RNAs (ncRNAs) in the Listeria genome and provided insight into an unexpected complex transcriptional machinery. In this review, we discuss ncRNAs that are encoded on the opposite strand of the target gene and are therefore termed antisense RNAs (asRNAs). We highlight mechanistic and functional concepts of asRNAs in L. monocytogenes and put these in context of asRNAs in other bacteria. Understanding asRNAs will further broaden our knowledge of RNA-mediated gene regulation and may provide targets for diagnostic and antimicrobial development.

Indexed as

Gene Expression Regulation, BacterialListeria monocytogenesRNA, AntisenseRNA, BacterialRNA, AntisenseRNA, Bacterialantisense RNAasRNAbacteriaListeria monocytogenesnext generation sequencingregulation

Identifiers

PMID25325017
PMCPMC4179725
OpenAlexW2121731220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.