ArticleJournal of dermatological case reports2014
Melanoma of the oral cavity: pathogenesis, dermoscopy, clinical features, staging and management.
Article in Journal of dermatological case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 55 citations in OpenAlex.
- Unveiling the Importance of Early Detection of Oral Mucosal Melanoma with Non-Invasive Imaging Techniques.Diagnostics (Basel, Switzerland) · 2026Review
- From Malaise to Oral Pain: A Case Report on Oral Mucosal Melanoma.Case reports in dentistry · 2026Article
- Mucosal Melanoma of the Oral Cavity: Prognostic Factors Influencing Patient Survival Outcomes.Journal of clinical medicine · 2025Review
- Multifocal Oral Mucosal Melanoma with an Atypical Clinical Presentation.Dentistry journal · 2025Article
- Review
- Article
- Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma.International journal of molecular sciences · 2023Review
- Investigation of oncolytic effect of recombinant Newcastle disease virus in primary and metastatic oral melanoma.Medical oncology (Northwood, London, England) · 2023Article
- Overview of common oral lesions.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2022Review
- Non-Cutaneous Melanoma, Findings and Prognostic Value of FDG PET/CT: A Case Series of 23 patients and review of the literature.Asia Oceania journal of nuclear medicine & biology · 2022Article
- Cutaneous and Mucosal Melanomas of Uncommon Sites: Where Do We Stand Now?Journal of clinical medicine · 2021Review
- Mucosal Melanoma: Pathological Evolution, Pathway Dependency and Targeted Therapy.Frontiers in oncology · 2021Review
- Oral malignant melanoma.Journal of oral and maxillofacial pathology : JOMFP · 2020Article
- Phosphorylated Akt1 expression is associated with poor prognosis in cutaneous, oral and sinonasal melanomas.Oncotarget · 2018Article
- Osseous choristoma of the tongue: A case report with dermoscopic study.Molecular and clinical oncology · 2018Article
- Personalized Medicine in Malignant Melanoma: Towards Patient Tailored Treatment.Frontiers in oncology · 2018Review
- Gingival Leiomyosarcoma in a Young Woman: Case report and literature review.Sultan Qaboos University medical journal · 2017Review
- Certainty of S100 from Physiology to Pathology.Journal of clinical and diagnostic research : JCDR · 2016Review
- Photoletter to the editor: Exogenous pigmentation after Diplopoda exposure leading to a dermatoscopic parallel ridge pattern on the plantar region.Journal of dermatological case reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary mucosal melanoma of the oral cavity is an exceedingly rare neoplasm which is estimated to comprise 1-2% of all oral malignancies. In contrast to cutaneous melanomas, the risk factors and pathogenesis are poorly understood. The predominate localization of primary oral melanoma is hard palate and maxillary alveolus. Dermoscopy may be utilized as an adjunctive tool in the clinical differential diagnosis of oral mucosal melanoma whenever the lesion is accessible with a dermoscope. Surgery is the mainstay of treatment, but it may be challenging depending on the location of the tumor within the oral cavity and its size. Adjuvant therapy with dacarbazine, platinum analogs, nitrosoureas and interleukin-2 have been utilized with low response rates. Imatinib may be effective for patients with with c-Kit gene mutations. Sunitinib and dasatinib have been reported effective in selected cases. Vemurafenib and dabrafenib are targeted agents for patients with BRAF mutation-positive melanoma. Ipilimumab, an anti-cytotoxic T-lymphocyte antigen 4 antibody and pembrolizumab, a monoclonal antibody targeting programmed death 1 receptor may be a feasible treatment option in patients with metastatic mucosal melanoma.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.