ReviewKorean journal of pediatrics2014
Febrile seizures.
Review in Korean journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Association between high-mobility group box 1 levels and febrile seizures in children: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- The prevalence and determinants of epilepsy in Ghana: A population-based study in two districts using a three-stage approach.Epilepsia · 2026Article
- Recurrence of febrile convulsions in children treated with intermittent benzodiazepines: a retrospective study investigating predisposing factors.BMC pediatrics · 2026Article
- The genotypic spectrum of complex febrile seizures: insights from high-risk population genetic screening in a pediatric cohort.Frontiers in neuroscience · 2026Article
- Novel serum biomarker for powerfully predicting pediatric simple febrile seizures.Frontiers in pediatrics · 2025Article
- Effect of environmental exposome and influenza infection on febrile seizure in children over 22 years: a time series analysis.International journal of biometeorology · 2024Article
- Article
- An overview of risk factors in children with febrile seizures.La Tunisie medicale · 2024Review
- Increased thrombospondin-1 levels contribute to epileptic susceptibility in neonatal hyperthermia without seizures via altered synaptogenesis.Cell death discovery · 2024Article
- Impact of Respiratory Viruses and SARS-CoV-2 on Febrile Seizures in Saudi Children: Insights into Etiologies, Gender, and Familial Associations.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Review
- Article
- Febrile seizures and convulsions with mild gastroenteritis: age-dependent acute symptomatic seizures.Frontiers in pediatrics · 2023Review
- The Negative Association between Breastfeeding Duration and Infant Febrile Seizure: A Retrospective Case-Control Study.International journal of environmental research and public health · 2022Article
- Prevalence, Risk Factors, and Outcomes of Influenza-Associated Neurologic Complications in Children.The Journal of pediatrics · 2021Article
- [Dynamic change of hippocampal volume in children with recurrent febrile seizures].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Exploring Variances of White Matter Integrity and the Glymphatic System in Simple Febrile Seizures and Epilepsy.Frontiers in neurology · 2021Article
- Assessing safety of Ontario's publicly funded MMR and MMRV immunization programs, 2012 to 2016.Paediatrics & child health · 2020Article
- Association between Foramen Size and Febrile Seizure Status in the Pediatric Population: A Two-Center Retrospective Analysis.Journal of neurosciences in rural practice · 2020Article
- The Pathogenesis of Fever-Induced Febrile Seizures and Its Current State.Neuroscience insights · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Febrile seizure (FS) is the most common seizure disorder of childhood, and occurs in an age-related manner. FS are classified into simple and complex. FS has a multifactorial inheritance, suggesting that both genetic and environmental factors are causative. Various animal models have elucidated the pathophysiological mechanisms of FS. Risk factors for a first FS are a family history of the disorder and a developmental delay. Risk factors for recurrent FS are a family history, age below 18 months at seizure onset, maximum temperature, and duration of fever. Risk factors for subsequent development of epilepsy are neurodevelopmental abnormality and complex FS. Clinicians evaluating children after a simple FS should concentrate on identifying the cause of the child's fever. Meningitis should be considered in the differential diagnosis for any febrile child. A simple FS does not usually require further evaluation such as ordering electroencephalography, neuroimaging, or other studies. Treatment is acute rescue therapy for prolonged FS. Antipyretics are not proven to reduce the recurrence risk for FS. Some evidence shows that both intermittent therapy with oral/rectal diazepam and continuous prophylaxis with oral phenobarbital or valproate are effective in reducing the risk of recurrence, but there is no evidence that these medications reduce the risk of subsequent epilepsy. Vaccine-induced FS is a rare event that does not lead to deleterious outcomes, but could affect patient and physician attitudes toward the safety of vaccination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.