Evidence map›Paper›PMID 25324723›Full record

ReviewFrontiers in cellular neuroscience2014

Synapses as therapeutic targets for autism spectrum disorders: an international symposium held in pavia on july 4th, 2014.

Paolo Curatolo, Yehezkel Ben-Ari, Yuri Bozzi, Maria Vincenza Catania, Egidio D'Angelo, Lisa Mapelli, Lindsay M Oberman, Christian Rosenmund, Enrico Cherubini

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cellular neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Hyperexcitability and Hyperplasticity Disrupt Cerebellar Signal Transfer in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  4. Article
  5. GABA and glycine in the developing brain.The journal of physiological sciences : JPS · 2016
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paolo CuratoloPediatric Neurology Unit, Department of Neurosciences, Tor Vergata University , Rome , Italy.
Yehezkel Ben-AriInstitut National de la Santé et de la Recherche Médicale, Mediterranean Institute of Neurobiology (INMED) , Marseille , France.
Yuri BozziCNR Neuroscience Institute and Laboratory of Molecular Neuropathology, Centre for Integrative Biology (CIBIO), University of Trento , Trento , Italy.
Maria Vincenza CataniaCNR, Institute of Neurological Sciences (ISN) , Catania , Italy ; Laboratory of Neurobiology, Istituto di Ricovero e Cura a Carattere Scientifico Oasi Maria SS , Troina , Italy.
Egidio D'AngeloDepartment of Brain and Behavioral Sciences, University of Pavia , Pavia , Italy ; Brain Connectivity Center, Neurological Institute Istituto di Ricovero e Cura a Carattere Scientifico Mondino , Pavia , Italy.
Lisa MapelliDepartment of Brain and Behavioral Sciences, University of Pavia , Pavia , Italy.
Lindsay M ObermanDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University , Providence, RI , USA.
Christian RosenmundNeuroscience Research Center and NeuroCure Cluster of Excellence, Charité-Universitätsmedizin Berlin , Berlin , Germany.
Enrico CherubiniInternational School for Advanced Studies (SISSA) , Trieste , Italy ; European Brain Research Institute (EBRI) , Rome , Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New progresses into the molecular and cellular mechanisms of autism spectrum disorders (ASDs) have been discussed in 1 day international symposium held in Pavia (Italy) on July 4th, 2014 entitled "synapses as therapeutic targets for autism spectrum disorders" (satellite of the FENS Forum for Neuroscience, Milan, 2014). In particular, world experts in the field have highlighted how animal models of ASDs have greatly advanced our understanding of the molecular pathways involved in synaptic dysfunction leading sometimes to "synaptic clinical trials" in children.

Indexed as

animal modelsASDsGABAergic signalingsynapsetherapeutic target

Identifiers

PMID25324723
PMCPMC4179609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.