Evidence map›Paper›PMID 25324699›Full record

ArticleInternational journal of biomedical science : IJBS2014

Potential Beneficial Effects of Si-Wu-Tang on White Blood Cell Numbers and the Gastrointestinal Tract of γ-Ray Irradiated Mice.

Jin Ni, Ana L Romero-Weaver, Ann R Kennedy

Open access · greenAbstract read
In one paragraph

Article in International journal of biomedical science : IJBS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jin NiDepartment of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA; ; Current Address: Department of Radiation Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, China.
Ana L Romero-WeaverDepartment of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA;
Ann R KennedyDepartment of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA;
University of Pennsylvania · US

Funding

RADIATION BIOLOGY TRAINING GRANTT32CA009677 · NCI · UNIVERSITY OF PENNSYLVANIA · PI KENNEDY, ANN R · 1992 to 2011
$5.0M
NCI NIH HHS T32 CA009677
6 · The paper itself

Abstract

Si-Wu-Tang (SWT) is a decoction consisting of a mixture of ingredients of Rehmanniae Radix, Angelica Radix, Chuanxiong Rhizoma and Paeoniae Radix. As a traditional Chinese herbal decoction, SWT has been widely used for the treatment of diseases characterized as blood and/or energy deficit. The present study was performed to evaluate the effects of SWT on the different populations of circulating white blood cells (WBCs) and gastrointestinal changes in γ-ray irradiated mice. Female mice were treated daily with orally administered SWT seven days before irradiation, until one day before irradiation or until one day before sample collection. WBC counts were determined from peripheral blood samples taken from the mice at different times post-irradiation. Hematoxylin and eosin (H&E) staining, as well as immunohistochemical analysis of fibrinogen, were utilized to evaluate the effects of SWT in the intestines of mice after radiation exposure. The results of the present studies demonstrate that SWT has protective effects against radiation damage to circulating WBCs, specifically to lymphocytes, and to the gastrointestinal tract of the irradiated animals.

Indexed as

fibrinogengamma radiationgastrointestinal tractgranulocyteslymphocytesmonocytesSi-Wu-Tangwhite blood cells

Identifiers

PMID25324699
PMCPMC4199477
OpenAlexW215297518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.