ArticleMagnetic resonance in medicine2015
Free-breathing combined three-dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization.
Article in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Free-Running Three-Dimensional Cardiac Extracellular Volume Mapping in a Single Scan With Mid-Scan Contrast Injection.Magnetic resonance in medicine · 2026Article
- The Evolving Role of Cardiac Imaging in Hypertrophic Cardiomyopathy: Diagnosis, Prognosis, and Clinical Practice.Biomedicines · 2025Review
- Free-breathing 3D cardiac extracellular volume (ECV) mapping using a linear tangent space alignment (LTSA) model.Magnetic resonance in medicine · 2025Article
- An Overview of Deep Learning Methods for Left Ventricle Segmentation.Computational intelligence and neuroscience · 2023Review
- Free-breathing 3D cardiac TMagnetic resonance in medicine · 2022Article
- Accelerated cardiac TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022Article
- Accelerating whole-heart 3D T2 mapping: Impact of undersampling strategies and reconstruction techniques.PloS one · 2021Article
- Whole-heart TMagnetic resonance in medicine · 2020Article
- Free-running 3D whole heart myocardial TMagnetic resonance in medicine · 2019Article
- Three-dimensional free breathing whole heart cardiovascular magnetic resonance TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018Article
- Temporally resolved parametric assessment of Z-magnetization recovery (TOPAZ): Dynamic myocardial TMagnetic resonance in medicine · 2018Article
- An Overview on Image Registration Techniques for Cardiac Diagnosis and Treatment.Cardiology research and practice · 2018Review
- Simultaneous multislice imaging for native myocardial TMagnetic resonance in medicine · 2017Article
- Black-blood native TMagnetic resonance in medicine · 2017Article
- Motion-robust cardiac B1+ mapping at 3T using interleaved bloch-siegert shifts.Magnetic resonance in medicine · 2017Article
- Improved border sharpness of post-infarct scar by a novel self-navigated free-breathing high-resolution 3D whole-heart inversion recovery magnetic resonance approach.The international journal of cardiovascular imaging · 2016Article
- Comparison of spoiled gradient echo and steady-state free-precession imaging for native myocardial T1 mapping using the slice-interleaved T1 mapping (STONE) sequence.NMR in biomedicine · 2016Article
- Sparse Reconstruction Techniques in Magnetic Resonance Imaging: Methods, Applications, and Challenges to Clinical Adoption.Investigative radiology · 2016Review
- A swine model of infarct-related reentrant ventricular tachycardia: Electroanatomic, magnetic resonance, and histopathological characterization.Heart rhythm · 2016Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo develop a novel MR sequence for combined three-dimensional (3D) phase-sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis.
methodsIn the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three-fold under-sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator-gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal-polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS-LGE images. The accuracy of the proposed method was assessed with respect to a inversion-recovery spin-echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look-Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging.
resultsThe deviation of the proposed method and the spin-echo reference was < 11 ms in phantom for T1 times between 250 and 600 ms, regardless of the inversion time selected in the LGE image. There was no significant difference in the in vivo T1 times of the proposed sequence and the 2D MOLLI technique (myocardium: 292 ± 75 ms versus 310 ± 49 ms, blood-pools: 191 ± 75 ms versus 182.0 ± 33). The LGE images showed proper nulling of the healthy myocardium in all subjects and clear depiction of scar in the patient.
conclusionThe proposed sequence enables simultaneous acquisition of 3D PS-LGE images and spatially registered 3D T1 maps in a single scan.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.