Evidence map›Paper›PMID 25324010›Full record

ArticleOrganic letters2014

Synthesis of unnatural amino acids functionalized with sterically shielded pyrroline nitroxides.

Ying Wang, Joseph T Paletta, Kathleen Berg, Erin Reinhart, Suchada Rajca, Andrzej Rajca

Abstract read
In one paragraph

Article in Organic letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Synthesis and Properties of (1International journal of molecular sciences · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Effects of FeInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying WangDepartment of Chemistry, University of Nebraska , Lincoln, Nebraska 68588-0304, United States.
Joseph T Paletta
Kathleen Berg
Erin Reinhart
Suchada Rajca
Andrzej Rajca

Funding

Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI NAKAMOTO, ROBERT K. · 2010 to 2017
$31.9M
NIGMS NIH HHS U54 GM087519NIGMS NIH HHS U54GM087519
6 · The paper itself

Abstract

A series of unnatural amino acids functionalized with sterically shielded pyrroline nitroxides were synthesized. Their reduction by ascorbate/glutathione indicates that L-cysteine functionalized with gem-diethylpyrroline nitroxide is reduced at the slowest rate and is comparable to that measured for the most resistant to reduction pyrroline and pyrrolidine nitroxides.

Indexed as

Amino AcidsAscorbic AcidCyclic N-OxidesCysteineGlutathioneMolecular StructureOxidation-ReductionPyrrolesPyrrolidinesStereoisomerismAmino AcidsAscorbic AcidCyclic N-OxidesCysteineGlutathionePyrrolespyrrolidinePyrrolidinespyrroline

Identifiers

PMID25324010
PMCPMC4201325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.