ArticleYonsei medical journal2014
Coxsackievirus B infection is highly related with missed abortion in Korea.
Article in Yonsei medical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Enterovirus Placentitis is an Underrecognized Cause of Placental Pathology.The American journal of surgical pathology · 2025Article
- Coxsackievirus B3 Infection of Human iPSC Lines and Derived Primary Germ-Layer Cells Regarding Receptor Expression.International journal of molecular sciences · 2021Article
- The expression and clinical significance of three lncRNAs in patients with a missed abortion.Experimental and therapeutic medicine · 2021Article
- Imbalance of the Gut Microbiota May Be Associated with Missed Abortions: A Perspective Study from a General Hospital of Hunan Province.Journal of immunology research · 2021Article
- Recent Updates on Research Models and Tools to Study Virus-Host Interactions at the Placenta.Viruses · 2019Review
- Pancreas of coxsackievirus-infected dams and their challenged pups: A complex issue.Virulence · 2019Article
- Expression of galectin-3 and apoptosis in placental villi from patients with missed abortion during early pregnancy.Experimental and therapeutic medicine · 2019Article
- Coxsackievirus B4 vertical transmission in a murine model.Virology journal · 2017Article
- Coxsackievirus B3 infection reduces female mouse fertility.Experimental animals · 2015Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study investigated the possible relationship between viral infection and first trimester pregnancy loss. MATERIALS AND
methodsA prospective study was performed on 51 gravidas with missed abortion, fetal anomaly, pre-term delivery, and full-tem delivery at Hanyang University Hospital. Enteroviruses were detected by semi-nested reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry in abortive tissues and placentas. Enterovirus serotypes were confirmed by genome sequencing. Herpesviruses were detected by PCR.
resultsCoxsackievirus B3 (CVB3) was detected in 8 of 14 missed abortion cases, 1 of 27 full-term cases, and none of the 9 pre-term cases. Coxsackievirus B1 (CVB1) was detected in an encephalocele case. Herpes simplex virus type 1 was found in 4 full-term cases, 3 pre-term cases, and none of the missed abortion cases.
conclusionThe prevalence of CVB3 was significantly higher in missed abortion cases compared to full-term or pre-term delivery cases. CVB infection may therefore be an important etiological agent of missed abortion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.