Evidence map›Paper›PMID 25323890›Full record

Trial reportYonsei medical journal2014

Comparison of the efficacy and safety of sodium phosphate tablets and polyethylene glycol solution for bowel cleansing in healthy Korean adults.

Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Sang-Wook Seo, Joon-Koo Kang, Eun-Hye Lee, Dong-Ryul Lee

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Yonsei medical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. The Effects and Adverse Reactions of Different Bowel Cleansers on Gut Microbiota After Colonoscopy.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Review
  9. Review
  10. Article
  11. A Modified Bowel Preparation Regimen for Colonoscopy Providing the Patients' Satisfaction and Convenience.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Seung-Hwa LeeHealth Promotion Center, Ajou University School of Medicine, Suwon, Korea.
Duck-Joo LeeHealth Promotion Center, Ajou University School of Medicine, Suwon, Korea. djleemd@medicus.co.kr.
Kwang-Min KimHealth Promotion Center, Ajou University School of Medicine, Suwon, Korea.
Sang-Wook SeoHealth Promotion Center, Ajou University School of Medicine, Suwon, Korea.
Joon-Koo KangDepartment of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
Eun-Hye LeeDepartment of Anesthesiology, Seoul National University College of Medicine, Seoul, Korea.
Dong-Ryul LeeHealth Promotion Center, Wonkwang University College of Medicine, Gunpo, Korea.
Ajou University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBowel cleansing is generally regarded as time-consuming and unpleasant among patients. Patients commonly state that bowel preparation provokes more discomfort than the actual colonoscopic examination. The purpose of this study was to compare two regimens of sodium phosphate (NaP) tablets versus polyethylene glycol (PEG) solution for bowel preparation in healthy Korean adults. MATERIALS AND

methodsThis was a single center, prospective, open-label, investigator-blinded, randomized, controlled-pilot study. A total of 62 healthy Korean subjects were randomly assigned to two groups (NaP vs. PEG). Efficacy, safety, and patient-related outcomes, as well as procedural parameters, were evaluated.

resultsAlthough there were no significant differences in total Ottawa bowel quality score, fluid scores and the rate of adequate bowel preparation were significantly better in the NaP group than the PEG group. Additionally, the NaP group showed better results regarding patient tolerance, satisfaction, preference, and rate of adverse events than the PEG group. Significant fluctuations in specific serum electrolytes were common and of a greater magnitude in the NaP group than the PEG group. However, these abnormalities were transient and did not result in serious complications and side effects.

conclusionIn this study, NaP tablets were shown to be an effective, well-tolerated, and acceptable regimen for bowel preparation. Also, our study suggests that NaP tablets may be safe and can be used as a bowel cleansing agent in healthy adults undergoing elective colonoscopy. Further multicenter, large scale studies are needed to confirm these findings.

Indexed as

ColonoscopyAdultAsian PeopleFemaleHumansMaleMiddle AgedPhosphatesPilot ProjectsPolyethylene GlycolsProspective StudiesRepublic of KoreaSurface-Active AgentsTabletsTherapeutic IrrigationPhosphatesPolyethylene Glycolssodium phosphateSurface-Active AgentsTabletsbowel preparationefficacypolyethylene glycolsafetySodium phosphate tablet

Identifiers

PMID25323890
PMCPMC4205693
OpenAlexW1992738846

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.