Evidence map›Paper›PMID 25323631›Full record

ArticleEpidemiology and infection2015

Modelling the epidemic spread of an H1N1 influenza outbreak in a rural university town.

N K Vaidya, M Morgan, T Jones, L Miller, S Lapin, E J Schwartz

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

N K VaidyaDepartment of Mathematics and Statistics,University of Missouri - Kansas City,Kansas City,MO,USA.
M MorganDepartment of Mathematics,School of Biological Sciences,Washington State University,Pullman,WA,USA.
T JonesSchool of Biological Sciences,Washington State University,Pullman,WA,USA.
L MillerDepartment of Mathematics,School of Biological Sciences,Washington State University,Pullman,WA,USA.
S LapinDepartment of Mathematics,School of Biological Sciences,Washington State University,Pullman,WA,USA.
E J SchwartzDepartment of Mathematics,School of Biological Sciences,Washington State University,Pullman,WA,USA.
Washington State University · USUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knowledge of mechanisms of infection in vulnerable populations is needed in order to prepare for future outbreaks. Here, using a unique dataset collected during a 2009 outbreak of influenza A(H1N1)pdm09 in a university town, we evaluated mechanisms of infection and identified that an epidemiological model containing partial protection of susceptibles best describes H1N1 dynamics in a rural university environment. We found that the protected group was over 14 times less susceptible to H1N1 infection than unprotected susceptibles. Our estimates show that the basic reproductive rate, R 0, was 5·96 (95% confidence interval 5·83-6·61), and, importantly, R 0 could be decreased to below 1 and similar epidemics could be avoided by increasing the proportion of the initial protected group. Moreover, several weeks into the epidemic, this protected group generated more new infections than the unprotected susceptible group, and thus, such protected groups should be taken into account while studying influenza epidemics in similar settings.

Indexed as

Influenza A Virus, H1N1 SubtypeRural PopulationUniversitiesAdolescentAdultEpidemicsHumansInfluenza, HumanModels, TheoreticalUnited StatesYoung Adultuniversity setting

Identifiers

PMID25323631
PMCPMC9507230
OpenAlexW2112780594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.