Evidence map›Paper›PMID 25323602›Full record

ArticleEuropean radiology2015

Cerebral aneurysm treatment using flow-diverting stents: in-vivo visualization of flow alterations by parametric colour coding to predict aneurysmal occlusion: preliminary results.

Philipp Gölitz, Tobias Struffert, Julie Rösch, Oliver Ganslandt, Frauke Knossalla, Arnd Doerfler

Abstract read
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In one paragraph

Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Flow-diverting stents allow efficient treatment of unruptured, intradural dissecting aneurysms of the vertebral artery: An explanatory approach using in vivo flow analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2016
    Trial
  3. Article
  4. Article
  5. Article
  6. Retrospective analysis of intracranial aneurysms after flow diverter treatment including color-coded imaging (syngo iFlow) as a predictor of aneurysm occlusion.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
  7. Article
  8. Angiographic assessment of the efficacy of flow diverter treatment for cerebral aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019
    Article
  9. In vitro angiographic comparison of the flow-diversion performance of five neurovascular stents.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2018
    Article
  10. Computation of the change in length of a braided device when deployed in realistic vessel models.International journal of computer assisted radiology and surgery · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Philipp GölitzDepartment of Neuroradiology, University of Erlangen- Nuremberg, Schwabachanlage 6, 91052, Erlangen, Germany, philipp.goelitz@uk-erlangen.de.
Tobias Struffert
Julie Rösch
Oliver Ganslandt
Frauke Knossalla
Arnd Doerfler
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAfter deployment of flow-diverting stents (FDS), complete aneurysm occlusion is not predictable. This study investigated whether parametric colour coding (PCC) could allow in vivo visualization of flow alterations induced by FDS and identify favourable or adverse flow modulations.

methodsThirty-six patients treated by FDS were analyzed. Preinterventional and postinterventional DSA-series were postprocessed by PCC and time-density curves (TDCs) were calculated. The parameters aneurysmal inflow, outflow, and relative time-to-peak (rTTP) were calculated. Preinterventional and postinterventional values were compared and related to occlusion rate.

resultsPostinterventional inflow showed a mean reduction of 37%, outflow of 51%, and rTTP a prolongation of 82%. Saccular aneurysm occlusion occurred if a reduction of at least 15% was achieved for inflow and 35% for outflow (sensitivity: 89%, specificity: 82%). Unchanged outflow and a slightly prolonged rTTP were associated with growth in one fusiform aneurysm.

conclusionsPCC allows visualization of flow alterations after FDS treatment, illustrating "flow diverting effects" by the TDC shape and indicating mainly aneurysmal outflow and lesser inflow changes. Quantifiable parameters (inflow, outflow, rTTP) can be obtained, thresholds for predicting aneurysm occlusion determined, and adverse flow modulations assumed. As a rapid intraprocedural tool, PCC might support the decision to implant more than one FDS. KEY POINTS: • After deployment of a flow-diverting stent, complete aneurysm occlusion is unpredictable. • Parametric colour coding offers new options for visualizing in vivo flow alterations non-invasively. • Quantifiable parameters, i.e., aneurysmal inflow/outflow can be obtained allowing prognostic stratification. • Rapid, intraprocedural application allows treatment monitoring, potentially contributing to patient safety.

Indexed as

Regional Blood FlowStentsAdultAgedAngiography, Digital SubtractionBlood Vessel Prosthesis ImplantationCerebrovascular CirculationFemaleFollow-Up StudiesHumansIntracranial AneurysmMaleMiddle AgedPrognosisProsthesis Design

Identifiers

PMID25323602
OpenAlexW2017698584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.