Evidence map›Paper›PMID 25323298›Full record

ReviewCurrent HIV/AIDS reports2014

Enhancing linkage and retention in HIV care: a review of interventions for highly resourced and resource-poor settings.

N Lance Okeke, Jan Ostermann, Nathan M Thielman

Registry-linked trialAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02692027 (Same Day Community-based ART Initiation Versus Clinic-based Pre-ART Assessment and Counselling for Individuals Newly Tested HIV-positive During Community-based HIV Testing in Rural Lesotho - a Randomized Controlled Trial), which is not on this map. Cited by 57 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02692027 phase3completednot on this mapstarted 2016, after this paper: background citation

Same Day Community-based ART Initiation Versus Clinic-based Pre-ART Assessment and Counselling for Individuals Newly Tested HIV-positive During Community-based HIV Testing in Rural Lesotho - a Randomized Controlled Trial

TypeinterventionalSponsorSwiss Tropical & Public Health InstituteRan2016 to 2018Enrolled276ConditionsHIV InfectionArmsSame-day ART initiation, Standard of care
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  17. A Comparative Analysis of Physical and Mobile Phone Tracing in Clinical Trials in Lilongwe, Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

N Lance OkekeDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USA, lance.okeke@duke.edu.
Jan Ostermann
Nathan M Thielman

Funding

Ruth L. Kirschstein National Research Service Award (NRSA)- T32T32AI007392 · NIAID · DUKE UNIVERSITY · PI Amy Lynn Corneli, Guido Ferrari · 1990 to 2026
$9.8M
NIAID NIH HHS T32 AI007392
6 · The paper itself

Abstract

Given the widespread availability of effective antiretroviral therapy, engagement of HIV-infected persons in care is a global priority. We reviewed 51 studies, published in the past decade, assessing strategies for improving linkage to and retention in HIV care. The review included studies from highly resourced settings (HRS) and resource-poor settings (RPS), specifically the USA and sub-Saharan Africa. In HRS, strength-based case management was best supported for improving linkage and retention in care; peer navigation and clinic-based health promotion were supported for improving retention. In RPS, point of care CD4 testing was best supported for improving linkage to care; decentralization, and task-shifting for improving retention. Novel interventions continue to emerge in HRS and RPS, yet many strategies have not been adequately evaluated. Further consideration should be given to analyses that identify which interventions, or combinations of interventions, are most effective, cost-effective, scalable, and aligned with patient preferences for HIV care.

Indexed as

Health PromotionPatient Acceptance of Health CarePatient ParticipationAfrica South of the SaharaAnti-Retroviral AgentsDeveloped CountriesDeveloping CountriesFemaleHealth ServicesHIV InfectionsHumansMalePatient-Centered CareUnited StatesAnti-Retroviral Agents

Identifiers

PMID25323298
PMCPMC5907797

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.