ArticleEuropean journal of cardiovascular nursing2015
Perceptions of family history and genetic testing and feasibility of pedigree development among African Americans with hypertension.
Article in European journal of cardiovascular nursing, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of race and ethnicity in views toward and participation in genetic studies and precision medicine research in the United States: A systematic review of qualitative and quantitative studies.Molecular genetics & genomic medicine · 2020Pooled it
- Exploring the use of family health histories in the African American community to reduce health disparities: Protocol for a randomized controlled trial.Contemporary clinical trials · 2026Article
- Creating a family health history interview protocol for use with undergraduate health professional students: A scoping review.Public health in practice (Oxford, England) · 2025Review
- Barriers, motivators and strategies to increase participation in genetic research among Asian and Black families of autistic individuals.Journal of community genetics · 2024Article
- Study protocol: Exploring the use of Family Health Histories in the African American community to reduce health disparities in Flint, Michigan.Research square · 2024Article
- Article
- Family health history and genetic services-the East Baltimore community stakeholder interview project.Journal of community genetics · 2019Article
- Structural and Contextual Patterns in Family Health History Knowledge among African American Adults: A Mixed-Methods Social Network Analysis Study.Journal of social structure : JOSS · 2019Article
- Pedigree Analysis of Polycystic Kidney Disease Patients: Bangladeshi Perspective.Indian journal of nephrologyArticle
- Article
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Abstract
backgroundPedigree development, family history, and genetic testing are thought to be useful in improving outcomes of chronic illnesses such as hypertension (HTN). However, the clinical utility of pedigree development is still unknown. Further, little is known about the perceptions of African Americans (AAs) of family history and genetic testing.
aimsThis study examined the feasibility of developing pedigrees for AAs with HTN and explored perceptions of family history and genetic research among AAs with HTN.
methodsThe US Surgeon General's My Family Health Portrait was administered, and 30-60 min in-person individual interviews were conducted. Descriptive statistics were used to analyze pedigree data. Interview transcripts were analyzed with content analysis and constant comparison.
resultsTwenty-nine AAs with HTN were recruited from one free clinic (15 women, 14 men; mean age 49 years, standard deviation (SD) 9.6). Twenty-six (90%) reported their family history in sufficient detail to develop a pedigree. Perceptions of family history included knowledge of HTN in the family, culturally influenced family teaching about HTN, and response to family history of HTN. Most participants agreed to future genetic testing and DNA collection because they wanted to help others; some said they needed more information and others expressed a concern for privacy.
conclusionThe majority of AAs in this sample possessed extensive knowledge of HTN within their family and were able to develop a three-generation pedigree with assistance. The majority were willing to participate in future genetic research.
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