Evidence map›Paper›PMID 25322686›Full record

Trial reportLeukemia2015

Genetic determinants of response and survival in momelotinib-treated patients with myelofibrosis.

A Pardanani, R A Abdelrahman, C Finke, T T Lasho, K H Begna, A Al-Kali, W J Hogan, M R Litzow, C A Hanson, R P Ketterling and 1 more

Abstract readClinical Trial, Phase IClinical Trial, Phase IILetter
In one paragraph

Trial report in Leukemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Targeting the JAK/STAT signalling axis in cancer: chemopreventive potential of natural compounds with emerging focus on retinoids.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  4. Advances in Stem Cell Transplantation for Myelofibrosis.Current hematologic malignancy reports · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Beyond JAK-STAT: novel therapeutic targets in Ph-negative MPN.Hematology. American Society of Hematology. Education Program · 2019
    Review
  13. Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2019
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Developmental Therapeutics in Myeloproliferative Neoplasms.Clinical lymphoma, myeloma & leukemia · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

A PardananiDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
R A AbdelrahmanDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
C FinkeDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
T T LashoDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
K H BegnaDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
A Al-KaliDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
W J HoganDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
M R LitzowDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
C A HansonDivision of Hematopathology, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
R P KetterlingDivision of Cytogenetics, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
A TefferiDivision of Hematology and Department of Medicine, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overBenzamidesCalreticulinDrug Administration ScheduleFemaleGene ExpressionGenetic MarkersHumansJanus Kinase 1Janus Kinase 2MaleMiddle AgedMutationPrimary MyelofibrosisASXL1 protein, humanBenzamidesCalreticulinCALR protein, humanGenetic MarkersJAK2 protein, humanJanus Kinase 1Janus Kinase 2MPL protein, humanN-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamideProtein Kinase InhibitorsPyrimidinesReceptors, ThrombopoietinRepressor Proteins

Identifiers

PMID25322686
PMCPMC4360208

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.