Trial reportNPJ primary care respiratory medicine2014
'The COPD breathlessness manual': a randomised controlled trial to test a cognitive-behavioural manual versus information booklets on health service use, mood and health status, in patients with chronic obstructive pulmonary disease.
Trial report in NPJ primary care respiratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Systematic review of effectiveness and quality assessment of patient education materials and decision aids for breathlessness.BMC pulmonary medicine · 2022Pooled it
- Self-management interventions for people with chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2022Pooled it
- Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2019Pooled it
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2018Pooled it
- Systematic review of the effectiveness of community-based self-management interventions among primary care COPD patients.NPJ primary care respiratory medicine · 2018Pooled it
- Effectiveness of village doctors led cognitive behavioral therapy for COPD patients in a randomized controlled trial.Scientific reports · 2025Trial
- A tailored psychological intervention for anxiety and depression management in people with chronic obstructive pulmonary disease: TANDEM RCT and process evaluation.Health technology assessment (Winchester, England) · 2024Trial
- A Mixed Methods Evaluation of a Pilot Multidisciplinary Breathlessness Support Service.Evaluation review · 2023Article
- Development and validation of a risk prediction model for anxiety or depression among patients with chronic obstructive pulmonary disease between 2018 and 2020.Annals of medicine · 2022Article
- Management of Refractory Breathlessness: a Review for General Internists.Journal of general internal medicine · 2021Review
- A Cognitive Behavioral Therapy-Informed Self-Management Program for Acute Respiratory Failure Survivors: A Feasibility Study.Journal of clinical medicine · 2021Article
- Palliative Care for People Living With Heart Disease-Does Sex Make a Difference?Frontiers in cardiovascular medicine · 2021Review
- Cognitive Behavioral Therapy for People with Chronic Obstructive Pulmonary Disease: Rapid Review.International journal of chronic obstructive pulmonary disease · 2020Review
- Improving the quality of life of people with advanced respiratory disease and severe breathlessness.Breathe (Sheffield, England) · 2019Review
- The role of cognitive behavioural therapy in living well with COPD.Breathe (Sheffield, England) · 2019Article
- Breathlessness services as a new model of support for patients with respiratory disease.Chronic respiratory disease · 2018Review
- The Breathing, Thinking, Functioning clinical model: a proposal to facilitate evidence-based breathlessness management in chronic respiratory disease.NPJ primary care respiratory medicine · 2017Review
- Strategies to improve anxiety and depression in patients with COPD: a mental health perspective.Neuropsychiatric disease and treatment · 2016Review
- Understanding fear and anxiety in patients at the time of an exacerbation of chronic obstructive pulmonary disease: a qualitative study.JRSM open · 2015Article
- Working in harmony with Nature: highlights from 2014, and a look to the future.NPJ primary care respiratory medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic obstructive pulmonary disease (COPD) is a costly long-term condition associated with frequent Accident and Emergency (A&E) and hospital admissions. Psychological difficulties and inadequate self-management can amplify this picture.
aimsTo compare a cognitive-behavioural manual versus information booklets (IB) on health service use, mood and health status.
methodsTwo hundred and twenty-two COPD patients were randomly allocated to receive either the COPD breathlessness manual (CM) or IB. They were instructed to work through their programme at home, over 5 weeks. Guidance from a facilitator was provided at an initial home visit plus two telephone call follow-ups.
resultsAfter 12 months, total A&E visits had reduced by 42% in the CM group, compared with a 16% rise in the IB group. The odds of people in the IB group attending A&E 12 months post-intervention was 1.9 times higher than for the CM group (CI 1.05-3.53). Reduction in hospital admissions and bed days were greatest in the CM group. At 6 months, there were significantly greater improvements in anxiety (F (2,198)=5.612, P=0.004), depression (F (1.8,176.1)=10.697, P⩽0.001) and dyspnoea (F (2,198)=18.170, P⩽0.001) in the CM group. Estimated savings at 12 months were greatest in the CM group, amounting to £30k or £270 per participant.
conclusionThe COPD manual, which addresses physical and mental health, is a straightforward cost-effective intervention that is worth offering to COPD patients within primary or secondary care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.