Evidence map›Paper›PMID 25321997›Full record

ArticleOptics express2014

High frame-rate multichannel beam-scanning microscopy based on Lissajous trajectories.

Shane Z Sullivan, Ryan D Muir, Justin A Newman, Mark S Carlsen, Suhas Sreehari, Chris Doerge, Nathan J Begue, R Michael Everly, Charles A Bouman, Garth J Simpson

Abstract read
In one paragraph

Article in Optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal.bioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Upscaling X-ray nanoimaging to macroscopic specimens.Journal of applied crystallography · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Design rules for dense and rapid Lissajous scanning.Microsystems & nanoengineering · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Multi-channel beam-scanning imaging at kHz frame rates by Lissajous trajectory microscopy.Proceedings of SPIE--the International Society for Optical Engineering · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shane Z Sullivan
Ryan D Muir
Justin A Newman
Mark S Carlsen
Suhas Sreehari
Chris Doerge
Nathan J Begue
R Michael Everly
Charles A Bouman
Garth J Simpson

Funding

Nonlinear Optical Imaging for Guiding Protein Structure DeterminationR01GM103401 · NIGMS · PURDUE UNIVERSITY · PI SIMPSON, GARTH JASON · 2012 to 2018
$1.7M
Ultrafast Nonlinear Optical Approaches toward High-Throughput Membrane Protein NaR01GM103910 · NIGMS · PURDUE UNIVERSITY · PI SIMPSON, GARTH JASON · 2013 to 2016
$1.1M
NIGMS NIH HHS R01 GM103401NIGMS NIH HHS R01GM-103401NIGMS NIH HHS R01 GM103910NIGMS NIH HHS R01GM-103910
6 · The paper itself

Abstract

A simple beam-scanning optical design based on Lissajous trajectory imaging is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In brief, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Since sub-trajectory and full-trajectory imaging are simply different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired. The optical hardware required to perform Lissajous imaging represents only a minor modification to established beam-scanning hardware, combined with additional control and data acquisition electronics. Preliminary studies based on laser transmittance imaging and polarization-dependent second harmonic generation microscopy support the viability of the approach both for detection of subtle changes in large signals and for trace-light detection of transient fluctuations.

Indexed as

AlgorithmsDiagnostic ImagingModels, TheoreticalPhantoms, ImagingHumansImage Processing, Computer-AssistedMicroscopy, Polarization

Identifiers

PMID25321997
PMCPMC4247188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.